Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11311905 | 0.77 | KMT2A (0.60) | KMT2AMEN1TSHRMAPK1MAPT | |
| SCHEMBL11318283 | 0.77 | KMT2A (0.50) | KMT2ATSHRMAPK1HTTRAB9A | |
| SCHEMBL20957602 | 0.76 | TSHR (0.51) | KMT2ATSHRMAPK1RAB9AALDH1A1 | |
| SCHEMBL5201425 | 0.73 | CES2 (0.54) | KMT2AMEN1MAPTNPSR1HTT | |
| SCHEMBL22612158 | 0.73 | NPC1 (0.43) | KMT2AMEN1TSHRMAPK1MAPT | |
| SCHEMBL28257505 | 0.72 | KMT2A (0.46) | KMT2ATSHRMAPK1MAPTRAB9A | |
| SCHEMBL6469132 | 0.72 | MEN1 (0.71) | KMT2AMEN1MAPK1MAPTHTT | |
| SCHEMBL3824409 | 0.72 | KMT2A (0.54) | KMT2AMEN1MAPK1MAPTATM | |
| SCHEMBL6832097 | 0.71 | KMT2A (0.56) | KMT2AMEN1TSHRMAPK1MAPT | |
| SCHEMBL9492815 | 0.71 | HTT (0.43) | KMT2AMEN1MAPTNPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004110351-A2 | HETEROCYCLIC COMPOUNDS FOR TREATING HEPATITIS C VIRUS | ANADYS PHARMACEUTICALS, INC. (US) | 2004-12-23 | — | — | WO | disclosed |