Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | PAM | P19021 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 3/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | PPARD | Q03181 | 4/20 | 0.42 |
| ▸ | PPARA | Q07869 | 4/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31285293 | 1.00 | DGKA (0.50) | DGKALMNAPAMMAPTMAPK1 | |
| SCHEMBL4936173 | 1.00 | DGKA (0.50) | DGKALMNAPAMMAPTMAPK1 | |
| SCHEMBL27321456 | 0.92 | DGKA (0.39) | DGKALMNAPAMMAPTMAPK1 | |
| Choline SCHEMBL28686393 | 0.87 | DGKA (0.39) | DGKALMNAMAPTMAPK1TSHR | |
| SCHEMBL1595383 | 0.85 | TSHR (0.44) | LMNATSHRALDH1A1PPARGPPARD | |
| SCHEMBL6309457 | 0.84 | ALDH1A1 (0.46) | LMNACES2CES1TSHRALDH1A1 | |
| SCHEMBL8865215 | 0.82 | DUT (0.35) | DGKALMNAALDH1A1DNM1 | |
| SCHEMBL9842180 | 0.82 | DGKA (0.47) | DGKALMNAPAMMAPTMAPK1 | |
| SCHEMBL6545278 | 0.82 | TSHR (0.38) | TSHR | |
| SCHEMBL4863534 | 0.81 | TSHR (0.31) | LMNATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294706-A1 | A PROCESS FOR LACTONIZATION TO PRODUCE SIMVASTATIN | Aurobindo Pharma Limited (IN) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002094804-A1 | A PROCESS FOR LACTONIZATION TO PRODUCE SIMVASTATIN | AUROBINDO PHARMA LIMITED (IN) | 2002-11-28 | — | — | WO | disclosed |