SCHEMBL7047458

SCHEMBL7047458

C=CC(=O)OCCN1C(=O)C(C)=C(C)C1=O

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.46
ALDH1A1 P00352 5/20 0.46
HPGD P15428 1/20 0.46
PKM P14618 1/20 0.46
TP53 P04637 3/20 0.46
HIF1A Q16665 3/20 0.46
HSD17B10 Q99714 3/20 0.46
CYP3A4 P08684 2/20 0.46
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
THRB P10828 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.36
GAA P10253 2/20 0.35
MAPK1 P28482 1/20 0.34
GLA P06280 1/20 0.33
BRCA1 P38398 1/20 0.33
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10065495 0.91 TSHR (0.58) TSHRALDH1A1HPGDPKMTP53
SCHEMBL10065496 0.91 TSHR (0.58) TSHRALDH1A1HPGDPKMTP53
SCHEMBL10065490 0.90 TSHR (0.52) TSHRALDH1A1HPGDPKMTP53
SCHEMBL17583279 0.89 TSHR (0.55) TSHRALDH1A1HPGDPKMTP53
SCHEMBL8052057 0.87 TSHR (0.58) TSHRALDH1A1HPGDPKMTP53
SCHEMBL15422951 0.85 TSHR (0.53) TSHRALDH1A1HPGDTP53HIF1A
SCHEMBL15422957 0.82 TSHR (0.46) TSHRALDH1A1HPGDPKMTP53
SCHEMBL16090941 0.80 MEN1 (0.46) TSHRALDH1A1PKMHSD17B10MEN1
SCHEMBL15423055 0.80 TSHR (0.40) TSHRALDH1A1HPGDTP53HIF1A
SCHEMBL1147831 0.79 TSHR (0.42) TSHRALDH1A1HPGDTP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0127574-B1 LIGHT CROSS-LINKABLE COMPOSITION CIBA-GEIGY AG (CH) 1987-10-07 EP claimed
EP-0062610-B1 PHOTOPOLYMERISATION PROCESS CIBA-GEIGY AG (CH) 1985-04-24 EP claimed
EP-0127574-A2 Light cross-linkable composition CIBA-GEIGY AG (CH) 1984-12-05 EP claimed
US-4416975-A Photopolymerization process employing compounds containing acryloyl groups and maleimide groups CIBA-GEIGY CORPORATION (US) 1983-11-22 US claimed
EP-0062610-A2 Photopolymerisation process CIBA-GEIGY AG (CH) 1982-10-13 EP claimed
US-10745570-B2 Copper-containing articles EASTMAN RODACK COMPANY (US) 2020-08-18 US disclosed
US-20190233660-A1 COPPER-CONTAINING ARTICLES BANK OF AMERICA, N.A., AS AGENT 2019-08-01 US disclosed
US-9963614-B2 Copper-containing articles and methods for providing same EASTMAN KODAK COMPANY (US) 2018-05-08 US disclosed
US-20160338358-A1 COPPER-CONTAINING POLYMERIC COMPOSITIONS KODAK AMERICAS, LTD. 2016-11-24 US disclosed
WO-2016186864-A1 COPPER-CONTAINING POLYMERIC COMPOSITIONS EASTMAN KODAK COMPANY (US) 2016-11-24 WO disclosed
US-20160340540-A1 COPPER-CONTAINING ARTICLES AND METHODS FOR PROVIDING SAME BANK OF AMERICA, N.A., AS AGENT 2016-11-24 US disclosed
US-9360759-B2 Forming conductive metal patterns using water-soluble polymers EASTMAN KODAK COMPANY (US) 2016-06-07 US disclosed
EP-0062610-B1 PHOTOPOLYMERISATION PROCESS CIBA-GEIGY AG (CH) 1985-04-24 EP disclosed
US-4500629-A Method of forming images from liquid masses CIBA-GEIGY CORPORATION (US) 1985-02-19 US disclosed
US-4440850-A Photopolymerisation process with two exposures of a single layer CIBA-GEIGY CORPORATION (US) 1984-04-03 US disclosed
EP-0102921-A2 Process for making images from liquid substances CIBA-GEIGY AG (CH) 1984-03-14 EP disclosed
US-4416975-A Photopolymerization process employing compounds containing acryloyl groups and maleimide groups CIBA-GEIGY CORPORATION (US) 1983-11-22 US disclosed
US-4416975-A Photopolymerization process employing compounds containing acryloyl groups and maleimide groups CIBA-GEIGY CORPORATION (US) 1983-11-22 US disclosed
EP-0062610-A2 Photopolymerisation process CIBA-GEIGY AG (CH) 1982-10-13 EP disclosed
EP-0062610-A2 Photopolymerisation process CIBA-GEIGY AG (CH) 1982-10-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160338358-A1 COPPER-CONTAINING POLYMERIC COMPOSITIONS CCNC, CTR9, PPOX TSHR 4365/4885ALDH1A1 511/4885HPGD 534/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.