SCHEMBL7047570

SCHEMBL7047570

Cc1ccccc1-c1ccc(OC(=O)Oc2ccc(-c3ccccc3C)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 3/20 0.52
PPARA Q07869 3/20 0.52
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA9 Q16790 1/20 0.47
MCL1 Q07820 1/20 0.46
KMT2A Q03164 4/20 0.43
MAPT P10636 2/20 0.43
MEN1 O00255 3/20 0.43
SLC1A3 P43003 1/20 0.41
SLC1A2 P43004 1/20 0.41
SLC1A1 P43005 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
FFAR1 O14842 3/20 0.40
FFAR4 Q5NUL3 1/20 0.40
EPHX1 P07099 1/20 0.40
SLC6A7 Q99884 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8682345 0.87 PPARG (0.55) PPARGPPARACA12CA1CA2
SCHEMBL1551128 0.87 LMNA (0.55) PPARGPPARACA12CA1CA2
SCHEMBL7647145 0.86 PPARG (0.50) PPARGPPARACA12CA1CA2
SCHEMBL28383281 0.84 KMT2A (0.53) PPARGPPARAMCL1KMT2AMAPT
SCHEMBL29819646 0.82 ELANE (0.56) PPARGPPARACA12CA1CA2
SCHEMBL16192607 0.82 ELANE (0.56) PPARGPPARACA12CA1CA2
SCHEMBL19470214 0.81 PPARA (0.42) PPARGPPARACA12CA1CA2
SCHEMBL1637928 0.78 CYP2A6 (0.52) KMT2AMAPTMEN1FFAR1
SCHEMBL8063641 0.77 ALDH1A1 (0.42) PPARGPPARAKMT2AMAPTMEN1
SCHEMBL7600285 0.77 PPARA (0.57) PPARGPPARACA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1300432-A1 Process for producing a polycarbonate and method of cleaning a production unit TEIJIN LIMITED (JP) 2003-04-09 EP disclosed
US-6525171-B2 Cleaning the aromatic polycarbonate continuous production unit with a carbonic acid diaryl ester at a temperature of 200-350 degrees C. in an inert gas atmosphere; ester interchange; discoloration inhibition TEIJIN LIMITED (JP) 2003-02-25 US disclosed
US-20020052467-A1 Process for producing a polycarbonate and method of cleaning a production unit TEIJIN LIMITED 2002-05-02 US disclosed