SCHEMBL8080220

SCHEMBL8080220

CCCCCCOc1cccc(C(=O)O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.82
PLA2G4B P0C869 3/20 0.82
SMPD1 P17405 3/20 0.74
PLA2G2A P14555 1/20 0.73
NR1H4 Q96RI1 2/20 0.73
TP53 P04637 1/20 0.69
TSHR P16473 1/20 0.69
PTPN11 Q06124 1/20 0.67
THRA P10827 1/20 0.67
THRB P10828 1/20 0.67
RARB P10826 3/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31661137 1.00 KMT2A (0.82) KMT2APLA2G4BSMPD1PLA2G2ANR1H4
SCHEMBL4652291 1.00 KMT2A (0.82) KMT2APLA2G4BSMPD1PLA2G2ANR1H4
SCHEMBL15766225 1.00 KMT2A (0.82) KMT2APLA2G4BSMPD1PLA2G2ANR1H4
SCHEMBL7822821 1.00 KMT2A (0.82) KMT2APLA2G4BSMPD1PLA2G2ANR1H4
SCHEMBL8081150 1.00 KMT2A (0.82) KMT2APLA2G4BSMPD1PLA2G2ANR1H4
SCHEMBL7047692 1.00 KMT2A (0.82) KMT2APLA2G4BSMPD1PLA2G2ANR1H4
SCHEMBL8082044 1.00 KMT2A (0.82) KMT2APLA2G4BSMPD1PLA2G2ANR1H4
SCHEMBL8086388 1.00 KMT2A (0.82) KMT2APLA2G4BSMPD1PLA2G2ANR1H4
SCHEMBL2887568 1.00 KMT2A (0.82) KMT2APLA2G4BSMPD1PLA2G2ANR1H4
SCHEMBL29758526 1.00 KMT2A (0.82) KMT2APLA2G4BSMPD1PLA2G2ANR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016058991-A1 POLYMERS FEATURING ENHANCED FLOW SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2016-04-21 WO claimed
US-20230205083-A1 SALT COMPOUND, RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-06-29 US disclosed
WO-2016058991-A1 POLYMERS FEATURING ENHANCED FLOW SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2016-04-21 WO disclosed
CN-104981452-A Skin whitening agent containing novel cyclic compound RNS CO LTD 2015-10-14 CN disclosed
US-8501037-B2 Optically anisotropic compound and resin composition comprising the same LG CHEM, LTD. (KR) 2013-08-06 US disclosed
US-8501037-B2 Optically anisotropic compound and resin composition comprising the same LG CHEM, LTD. (KR) 2013-08-06 US disclosed
US-20100130659-A1 OPTICALLY ANISOTROPIC COMPOUND AND RESIN COMPOSITION COMPRISING THE SAME LG CHEM, LTD. (KR) 2010-05-27 US disclosed
US-20100130659-A1 OPTICALLY ANISOTROPIC COMPOUND AND RESIN COMPOSITION COMPRISING THE SAME LG CHEM, LTD. (KR) 2010-05-27 US disclosed
WO-2009025484-A2 OPTICALLY ANISOTROPIC COMPOUND AND RESIN COMPOSITION COMPRISING THE SAME LG CHEM, LTD. (KR) 2009-02-26 WO disclosed
EP-0758013-B1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL CO LTD (JP) 2000-10-11 EP disclosed
US-5855971-A Liquid crystalline optical film, compensating film for liquid crystal display comprising the liquid crystalline optical film, and liquid crystal display having the compensating film NIPPON OIL COMPANY, LIMITED (JP) 1999-01-05 US disclosed
WO-1998043649-A2 AGE PRODUCTION INHIBITORY COMPOSITION COMPRISING A MAILLARD REACTION INHIBITOR AND VITAMIN B¿6? OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1998-10-08 WO disclosed
EP-0758013-A1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL COMPANY, LIMITED (JP) 1997-02-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230205083-A1 SALT COMPOUND, RESIST COMPOSITION AND PATTERNING PROCESS SLC6A9, SLC6A5, REN KMT2A 2175/4885PLA2G4B 2926/4885SMPD1 2729/4885
US-20100130659-A1 OPTICALLY ANISOTROPIC COMPOUND AND RESIN COMPOSITION COMPRISING THE SAME RCC1, RER1, MED1 KMT2A 1007/4885PLA2G4B 1904/4885SMPD1 3734/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.