Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7049034 | 1.00 | CCR2 (0.45) | CCR2ABCB11 | |
| SCHEMBL7047693 | 0.88 | CCR2 (0.48) | CCR2ABCB11 | |
| SCHEMBL7050840 | 0.81 | CCR2 (0.41) | CCR2ABCB11 | |
| SCHEMBL7050825 | 0.80 | CCR2 (0.39) | CCR2ABCB11 | |
| SCHEMBL7052377 | 0.80 | CCR2 (0.53) | CCR2ABCB11 | |
| SCHEMBL7947056 | 0.77 | CCR2 (0.55) | CCR2ABCB11 | |
| SCHEMBL7050361 | 0.76 | TSHR (0.43) | CCR2ABCB11 | |
| SCHEMBL7052102 | 0.76 | CCR2 (0.56) | CCR2ABCB11 | |
| SCHEMBL7048043 | 0.73 | BRD4 (0.44) | CCR2ABCB11 | |
| SCHEMBL7050228 | 0.71 | CCR2 (0.39) | CCR2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054667-B1 | BICYCLIC PYRROLE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE AS ANTIINFLAMMATORY AND IMMUNOMODULATING AGENTS | ASTRAZENECA UK LTD (GB) | 2003-04-16 | — | — | EP | disclosed |
| US-6291507-B1 | INHIBITOR OF MONOCYTE CHEMOATTRACTANT PROTEIN-1; INDOLE DERIVATIVES | ASTRAZENECA UK LIMITED (GB) | 2001-09-18 | — | — | US | disclosed |