Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 16/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052102 | 0.99 | CCR2 (0.56) | CCR2ABCB11 | |
| SCHEMBL12584599 | 0.87 | CCR2 (0.53) | CCR2LMNAMAPT | |
| SCHEMBL10592159 | 0.85 | CCR2 (0.52) | CCR2LMNARAB9A | |
| SCHEMBL7052377 | 0.85 | CCR2 (0.53) | CCR2ABCB11LMNAMAPTRAB9A | |
| SCHEMBL7969831 | 0.83 | MAPT (0.47) | CCR2ABCB11LMNAMAPTRAB9A | |
| SCHEMBL7047270 | 0.82 | MAPT (0.48) | CCR2ABCB11LMNAMAPTRAB9A | |
| SCHEMBL7049034 | 0.77 | CCR2 (0.45) | CCR2ABCB11 | |
| SCHEMBL7048041 | 0.77 | CCR2 (0.45) | CCR2ABCB11 | |
| SCHEMBL7047693 | 0.76 | CCR2 (0.48) | CCR2ABCB11 | |
| SCHEMBL1006638 | 0.73 | GPR35 (0.44) | LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291507-B1 | INHIBITOR OF MONOCYTE CHEMOATTRACTANT PROTEIN-1; INDOLE DERIVATIVES | ASTRAZENECA UK LIMITED (GB) | 2001-09-18 | — | — | US | disclosed |