SCHEMBL7048424

SCHEMBL7048424

CC(=O)c1ccc([N+]2(C)CCOCC2)cc1.C[N+]1(c2ccc(C=O)cc2)CCOCC1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.40
KDM4E B2RXH2 4/20 0.38
CYP1A1 P04798 1/20 0.38
KMT2A Q03164 1/20 0.36
MAPT P10636 4/20 0.35
ATM Q13315 1/20 0.35
USP2 O75604 1/20 0.35
PABPC1 P11940 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
LMNA P02545 1/20 0.35
CYP2C9 P11712 2/20 0.33
PTGS2 P35354 1/20 0.33
NPC1 O15118 1/20 0.33
CYP2C19 P33261 1/20 0.33
RAB9A P51151 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
PARP10 Q53GL7 1/20 0.33
PARP3 Q9Y6F1 1/20 0.33
POLB P06746 1/20 0.33
APOBEC3A P31941 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4626490 0.89 CYP2A6 (0.39) ALDH1A1KDM4ESMN1; SMN2
SCHEMBL4625538 0.89 KDM4E (0.45) ALDH1A1KDM4ECYP1A1KMT2AMAPT
SCHEMBL6848520 0.81 POLB (0.41) ALDH1A1KDM4ECYP1A1KMT2AMAPT
Nitric Acid SCHEMBL8345678 0.81 MAPK1 (0.45) ALDH1A1KDM4ECYP1A1KMT2AMAPT
SCHEMBL6843072 0.81 CYP2A6 (0.32) ALDH1A1KDM4ESMN1; SMN2
SCHEMBL97268 0.77 ALDH1A1 (0.62) ALDH1A1KDM4EKMT2AMAPTSMN1; SMN2
SCHEMBL6848030 0.75 ALDH1A1 (0.33) ALDH1A1KDM4E
SCHEMBL6843056 0.75 USP2 (0.38) ALDH1A1KDM4ECYP1A1KMT2AMAPT
SCHEMBL4626526 0.74 HPGD (0.54) ALDH1A1KMT2AMAPTATMSMN1; SMN2
SCHEMBL4626949 0.73 CYP2A6 (0.43) ALDH1A1KDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1300133-A2 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-09 EP claimed
EP-1300133-A2 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-09 EP disclosed