Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.38 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4661676 | 0.85 | MGAM (0.45) | GRIK1ALDH1A1SMN1; SMN2CYP2D6HPGD | |
| SCHEMBL6555623 | 0.84 | GRIK1 (0.43) | EGLN1GRIK1ALDH1A1GRIA1GRIA2 | |
| SCHEMBL13060426 | 0.82 | GRIK1 (0.42) | EGLN1GRIK1GRIA1GRIA2GRIA4 | |
| SCHEMBL27789732 | 0.81 | GRIK1 (0.38) | GRIK1ALDH1A1SMN1; SMN2GRIA1GRIA2 | |
| SCHEMBL14277683 | 0.78 | GRIK1 (0.42) | EGLN1GRIK1GRIA1GRIA2GRIA4 | |
| SCHEMBL28052037 | 0.78 | FAAH (0.37) | GRIK1ALDH1A1GRIA1GRIA2GRIA4 | |
| SCHEMBL13269286 | 0.76 | ALDH1A1 (0.39) | EGLN1ALDH1A1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL3179017 | 0.76 | MAPT (0.38) | EGLN1GRIK1ALDH1A1HPGDKDM4E | |
| SCHEMBL28661006 | 0.75 | GRIK1 (0.53) | GRIK1ALDH1A1SMN1; SMN2GRIA1GRIA2 | |
| SCHEMBL6356446 | 0.75 | GRIK1 (0.39) | EGLN1GRIK1ALDH1A1SMN1; SMN2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042270-B1 | ASYMMETRIC HYDROGENATION | CHIROTECH TECHNOLOGY LTD (GB) | 2003-04-09 | — | — | EP | disclosed |
| US-6207853-B1 | SUCCINIC ACID DERIVATIVE | CHIROTECH TECHNOLOGY, INC. (GB) | 2001-03-27 | — | — | US | disclosed |
| EP-1042270-A1 | ASYMMETRIC HYDROGENATION | Chirotech Technology Limited (GB) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999031041-A1 | ASYMMETRIC HYDROGENATION | CHIROTECH TECHNOLOGY LIMITED (GB) | 1999-06-24 | — | — | WO | disclosed |