SCHEMBL7048548

SCHEMBL7048548

CCCCC(C(=O)O)C(OC(c1ccccc1)(c1ccc(OC)cc1)c1ccc(OC)cc1)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 5/20 0.48
MMP1 P03956 1/20 0.40
MMP2 P08253 1/20 0.40
MMP3 P08254 1/20 0.40
ALDH1A1 P00352 1/20 0.39
KCNH2 Q12809 1/20 0.39
SLC6A1 P30531 2/20 0.39
SLC6A11 P48066 1/20 0.39
PPARG P37231 4/20 0.39
PPARA Q07869 4/20 0.39
ALOX5 P09917 3/20 0.39
CTSK P43235 1/20 0.39
MMP9 P14780 1/20 0.39
MMP13 P45452 1/20 0.39
TAS1R3 Q7RTX0 1/20 0.39
TAS1R1 Q7RTX1 1/20 0.39
CNR2 P34972 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27433687 0.74 PPARG (0.47) KIF11MMP1ALDH1A1PPARGPPARA
SCHEMBL29941907 0.73 PPARG (0.53) KIF11KCNH2PPARGPPARAALOX5
SCHEMBL4633665 0.73 KIF11 (0.43) KIF11SLC6A1SLC6A11PPARGPPARA
SCHEMBL10683949 0.72 KIF11 (0.39) KIF11MMP1MMP2MMP3KCNH2
SCHEMBL19731701 0.72 ASAH1 (0.52) ALDH1A1
SCHEMBL8454432 0.72 KIF11 (0.45) KIF11KCNH2CNR2
SCHEMBL28489645 0.72 KIF11 (0.46) KIF11MMP1MMP2MMP3ALDH1A1
SCHEMBL18486308 0.72 KIF11 (0.49) KIF11ALDH1A1KCNH2SLC6A1SLC6A11
SCHEMBL14516389 0.71 ALDH1A1 (0.49) KIF11ALDH1A1
SCHEMBL16197752 0.71 KIF11 (0.50) KIF11KCNH2SLC6A1SLC6A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1006121-B1 A universal polymer support for the synthesis of oligonucleotides COUNCIL SCIENT IND RES (IN) 2003-05-02 EP disclosed
US-6090934-A POLYMER SUPPORT CONTAINING AN ORGANIC ALIPHATIC MOLECULE OF GIVEN STRUCTURE HAVING A PAIR OF CIS-HYDROXYL GROUPS WHERE ONE HYDROXYL GROUP IS COVALENTLY ATTACHED TO THE POLYMER AND THE OTHER IS PROTECTED BY AN ACID LABILE GROUP COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2000-07-18 US disclosed
EP-1006121-A1 A universal polymer support for the synthesis of oligonucleotides Council of Scientific and Industrial Research (IN) 2000-06-07 EP disclosed
US-5942608-A REACTING ALKANEDIOL WITH 4,48-DIMETHOXY TRITYL CHLORIDE; THEN ALKANOIC ACID HALIDE; IMMOBILIZATION Council of Sciemtific & Industrial Research and Department of Biotechnology (IN) 1999-08-24 US disclosed