SCHEMBL8454432

SCHEMBL8454432

CCC([O])OC(c1ccccc1)(c1ccc(OC)cc1)c1ccc(OC)cc1

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 11/20 0.45
KCNH2 Q12809 1/20 0.44
LTA4H P09960 2/20 0.40
CA4 P22748 1/20 0.39
KMT2A Q03164 1/20 0.39
CNR2 P34972 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28489468 0.79 KIF11 (0.52) KIF11KCNH2LTA4HCA4
SCHEMBL21562153 0.78 CA4 (0.46) KIF11KCNH2LTA4HCA4KMT2A
SCHEMBL17173364 0.78 CA4 (0.46) KIF11KCNH2LTA4HCA4KMT2A
SCHEMBL715992 0.77 KIF11 (0.50) KIF11KCNH2LTA4HCA4
SCHEMBL28346610 0.76 KIF11 (0.44) KIF11KCNH2LTA4HCA4KMT2A
SCHEMBL13003134 0.75 KIF11 (0.50) KIF11KCNH2LTA4HCA4
SCHEMBL20644235 0.75 KIF11 (0.50) KIF11KCNH2LTA4HCA4
SCHEMBL8655114 0.75 KMT2A (0.42) KIF11KCNH2LTA4HCA4KMT2A
SCHEMBL10495868 0.75 KIF11 (0.45) KIF11KCNH2KMT2A
SCHEMBL4421575 0.75 KIF11 (0.45) KIF11KCNH2LTA4HKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0954612-A2 DNA DIAGNOSTICS BASED ON MASS SPECTROMETRY SEQUENOM, INC. (US) 1999-11-10 EP disclosed
EP-0937096-A2 HIGH DENSITY IMMOBILIZATION OF NUCLEIC ACIDS SEQUENOM, INC. (US) 1999-08-25 EP disclosed
WO-1998020020-A2 HIGH DENSITY IMMOBILIZATION OF NUCLEIC ACIDS SEQUENOM, INC. (US) 1998-05-14 WO disclosed
WO-1998020166-A2 DNA DIAGNOSTICS BASED ON MASS SPECTROMETRY SEQUENOM, INC. (US) 1998-05-14 WO disclosed