SCHEMBL7048684

SCHEMBL7048684

O=C(O)[C@H](CS)NC1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ PYGB P11216 7/20 0.49
▸ GAA P10253 1/20 0.49
▸ CA12 O43570 3/20 0.46
▸ CA1 P00915 3/20 0.46
▸ CA2 P00918 3/20 0.46
▸ CA9 Q16790 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8898692 0.98 PYGB (0.46) PYGBGAACA12CA1CA2
SCHEMBL29748594 0.88 CA12 (0.48) PYGBGAACA12CA1CA2
SCHEMBL29583329 0.88 CA12 (0.48) PYGBGAACA12CA1CA2
SCHEMBL3801496 0.87 PYGB (0.51) PYGBGAACA12CA1CA2
SCHEMBL20476841 0.87 PYGB (0.51) PYGBGAACA12CA1CA2
SCHEMBL27997210 0.87 PYGB (0.51) PYGBGAACA12CA1CA2
SCHEMBL2012475 0.87 PYGB (0.51) PYGBGAACA12CA1CA2
SCHEMBL28419458 0.87 PYGB (0.51) PYGBGAACA12CA1CA2
SCHEMBL867964 0.87 PYGB (0.51) PYGBGAACA12CA1CA2
SCHEMBL2354072 0.86 PYGB (0.44) PYGBGAACA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0721347-A1 AGENT AGAINST SENSITIVE, HYPERREACTIVE AND HYPOACTIVE STATES OF THE SKIN, FORMS OF ACNE, ATOPIC DERMATITIDES, PSORIASIS, PRURIGO, PHOTODERMATOSES, ICHTHYOSIS AND VIRAL INFECTIONS Beiersdorf Aktiengesellschaft (DE) 1996-07-17 — — EP claimed
WO-1995005852-A1 AGENT AGAINST SENSITIVE, HYPERREACTIVE AND HYPOACTIVE STATES OF THE SKIN, FORMS OF ACNE, ATOPIC DERMATITIDES, PSORIASIS, PRURIGO, PHOTODERMATOSES, ICHTHYOSIS AND VIRAL INFECTIONS BEIERSDORF AG (DE) 1995-03-02 — — WO claimed
CN-115427038-A Methods of treating nervous system symptoms associated with lysosomal storage diseases 建新公司 2022-12-02 — — CN disclosed
CN-113645969-A Methods for treating symptoms and disorders associated with lysosomal storage disorders 建新公司 2021-11-12 — — CN disclosed
EP-0797427-B1 AGENTS ACTING AGAINST HYPERREACTIVE AND HYPOACTIVE, DEFICIENT SKIN CONDITIONS AND MANIFEST DERMATITIDES BEIERSDORF AG (DE) 2003-05-14 — — EP disclosed
EP-1300138-A2 Agents effective against hyperreactive and hypoactive deficient skin conditions as well as manifest dermatitis Beiersdorf AG (DE) 2003-04-09 — — EP disclosed
US-6180662-B1 MIXTURE OF CINNAMIC ACID, ANTIOXIDANT, ENZYME, MICROBIOCIDES AND VIRICIDES BEIERSDORF AG (DE) 2001-01-30 — — US disclosed
US-5952373-A APPLYING TO THE SKIN AN EFFECTIVE AMOUNT OF ONE OR MORE FLAVONOIDS BEIERSDORF AG (DE) 1999-09-14 — — US disclosed
EP-0797427-A1 AGENTS ACTING AGAINST HYPERREACTIVE AND HYPOACTIVE, DEFICIENT SKIN CONDITIONS AND MANIFEST DERMATITIDES Beiersdorf Aktiengesellschaft (DE) 1997-10-01 — — EP disclosed
EP-0721347-A1 AGENT AGAINST SENSITIVE, HYPERREACTIVE AND HYPOACTIVE STATES OF THE SKIN, FORMS OF ACNE, ATOPIC DERMATITIDES, PSORIASIS, PRURIGO, PHOTODERMATOSES, ICHTHYOSIS AND VIRAL INFECTIONS Beiersdorf Aktiengesellschaft (DE) 1996-07-17 — — EP disclosed
WO-1996018381-A1 AGENTS ACTING AGAINST HYPERREACTIVE AND HYPOACTIVE, DEFICIENT SKIN CONDITIONS AND MANIFEST DERMATITIDES BEIERSDORF AG (DE) 1996-06-20 — — WO disclosed
WO-1995005852-A1 AGENT AGAINST SENSITIVE, HYPERREACTIVE AND HYPOACTIVE STATES OF THE SKIN, FORMS OF ACNE, ATOPIC DERMATITIDES, PSORIASIS, PRURIGO, PHOTODERMATOSES, ICHTHYOSIS AND VIRAL INFECTIONS BEIERSDORF AG (DE) 1995-03-02 — — WO disclosed
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