SCHEMBL20476841

SCHEMBL20476841

O=C(O)C(CO)NC1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ PYGB P11216 7/20 0.51
▸ GAA P10253 1/20 0.51
▸ CA12 O43570 3/20 0.49
▸ CA1 P00915 3/20 0.49
▸ CA2 P00918 3/20 0.49
▸ CA9 Q16790 3/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3801496 1.00 PYGB (0.51) PYGBGAACA12CA1CA2
SCHEMBL27997210 1.00 PYGB (0.51) PYGBGAACA12CA1CA2
SCHEMBL2012475 1.00 PYGB (0.51) PYGBGAACA12CA1CA2
SCHEMBL867964 1.00 PYGB (0.51) PYGBGAACA12CA1CA2
SCHEMBL28419458 1.00 PYGB (0.51) PYGBGAACA12CA1CA2
SCHEMBL29550937 0.98 PYGB (0.49) PYGBGAACA12CA1CA2
SCHEMBL7048684 0.87 PYGB (0.49) PYGBGAACA12CA1CA2
SCHEMBL2848040 0.86 PYGB (0.44) PYGBGAACA12CA1CA2
SCHEMBL4006332 0.86 PYGB (0.44) PYGBGAACA12CA1CA2
SCHEMBL670576 0.86 PYGB (0.44) PYGBGAACA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200131231-A1 CELL PENETRATING PEPTIDES UNITED KINGDOM RESEARCH AND INNOVATION (GB) 2020-04-30 — — US claimed
WO-2018150196-A1 CELL PENETRATING PEPTIDES MODIFIED BY GLYCOSYLATION OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2018-08-23 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200131231-A1 CELL PENETRATING PEPTIDES SLC3A2, ARGLU1, SLC1A5 PYGB 48/4885GAA 707/4885CA12 2207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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