SCHEMBL867964

SCHEMBL867964

O=C(O)[C@H](CO)NC1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ PYGB P11216 7/20 0.51
▸ GAA P10253 1/20 0.51
▸ CA12 O43570 3/20 0.49
▸ CA1 P00915 3/20 0.49
▸ CA2 P00918 3/20 0.49
▸ CA9 Q16790 3/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3801496 1.00 PYGB (0.51) PYGBGAACA12CA1CA2
SCHEMBL27997210 1.00 PYGB (0.51) PYGBGAACA12CA1CA2
SCHEMBL20476841 1.00 PYGB (0.51) PYGBGAACA12CA1CA2
SCHEMBL2012475 1.00 PYGB (0.51) PYGBGAACA12CA1CA2
SCHEMBL28419458 1.00 PYGB (0.51) PYGBGAACA12CA1CA2
SCHEMBL29550937 0.98 PYGB (0.49) PYGBGAACA12CA1CA2
SCHEMBL7048684 0.87 PYGB (0.49) PYGBGAACA12CA1CA2
SCHEMBL2848040 0.86 PYGB (0.44) PYGBGAACA12CA1CA2
SCHEMBL4006332 0.86 PYGB (0.44) PYGBGAACA12CA1CA2
SCHEMBL670576 0.86 PYGB (0.44) PYGBGAACA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4727356-A2 SYNTHETIC ANTIFREEZE GLYCOPROTEINS WITH ICE-BINDING ACTIVITY University of Utah Research Foundation (US) 2026-04-22 — — EP disclosed
WO-2024258965-A2 SYNTHETIC ANTIFREEZE GLYCOPROTEINS WITH ICE-BINDING ACTIVITY UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2024-12-19 — — WO disclosed
US-20230256080-A1 VACCINE AND THERAPEUTIC COMPOSITIONS COMPRISING ANTIGEN-CONJUGATED VIRAL CAPSIDS UNIV MICHIGAN STATE (US) 2023-08-17 — — US disclosed
US-8871468-B2 Synthetic genes for plant gums and other hydroxyproline-rich glycoproteins OHIO UNIVERSITY (US) 2014-10-28 — — US disclosed
US-20140287457-A9 SYNTHETIC GENES FOR PLANT GUMS AND OTHER HYDROXYPROLINE-RICH GLYCOPROTEINS NATIONAL SCIENCE FOUNDATION 2014-09-25 — — US disclosed
US-8623812-B2 Cross-linkable glycoproteins and methods of making the same OHIO UNIVERSITY (US) 2014-01-07 — — US disclosed
US-8563687-B2 Synthetic genes for plant gums and other hydroxyproline rich glycoproteins OHIO UNIVERSITY (US) 2013-10-22 — — US disclosed
US-20120077226-A1 SYNTHETIC GENES FOR PLANT GUMS AND OTHER HYDROXYPROLINE-RICH GLYCOPROTEINS KIELISZEWSKI MARCIA J (US) 2012-03-29 — — US disclosed
US-20110003340-A1 SYNTHETIC GENES FOR PLANT GUMS AND OTHER HYDROXYPROLINE-RICH PROTEINS KIELISZEWSKI MARCIA J 2011-01-06 — — US disclosed
US-20100261874-A1 SYNTHETIC GENES FOR PLANT GUMS AND OTHER HYDROXYPROLINE RICH GLYCOPROTEINS OHIO UNIVERSITY (US) 2010-10-14 — — US disclosed
US-20040009555-A1 Comprises nucleotide sequences coding gum arabic for use in food processing and cosmetics OHIO UNIVERSITY, TECHNOLOGY TRANSFER OFFICE, TECHNOLOGY AND ENTERPRISE BUILDING 2004-01-15 — — US disclosed
US-20040009557-A1 Novel synthetic genes for plant gums OHIO UNIVERSITY, TECHNOLOGY TRANSFER OFFICE, TECHNOLOGY AND ENTERPRISE BUILDING 2004-01-15 — — US disclosed
US-6639050-B1 Expression of synthetic genes designed from repetitive peptide sequences of hydroxyproline(Hyp)-rich glycoproteins (HRGPs), repetitive proline-rich proteins (RPRPs) and arabinogalactan-proteins OHIO UNIVERSITY 2003-10-28 — — US disclosed
US-6570062-B1 Nucleotide sequences coding plant gum for use in the generation of disease resistant and drought plants OHIO UNIVERSITY 2003-05-27 — — US disclosed
US-6548642-B1 Expression of synthetic genes designed from repetitive peptide sequences of hydroxyproline-rich glycoproteins OHIO UNIVERSITY 2003-04-15 — — US disclosed
WO-2001078503-A2 SYNTHETIC GENES FOR PLANT GUMS AND OTHER HYDROXYPROLINE-RICH GLYCOPROTEINS OHIO UNIVERSITY (US) 2001-10-25 — — WO disclosed
EP-1003840-A1 SYNTHETIC GENES FOR PLANT GUMS Ohio University (US) 2000-05-31 — — EP disclosed
WO-1999003978-A1 NOVEL SYNTHETIC GENES FOR PLANT GUMS OHIO UNIVERSITY (US) 1999-01-28 — — WO disclosed
EP-0736101-A1 ENZYMATIC METHOD FOR SYNTHESIS OF O-GLYCOSYLATED AMINO ACID OR PEPTIDE OR DERIVATIVES THEREOF BIOFLEXIN AB (SE) 1996-10-09 — — EP disclosed
WO-1995018232-A1 ENZYMATIC METHOD FOR SYNTHESIS OF O-GLYCOSYLATED AMINO ACID OR PEPTIDE OR DERIVATIVES THEREOF BIOFLEXIN AB (SE) 1995-07-06 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110003340-A1 SYNTHETIC GENES FOR PLANT GUMS AND OTHER HYDROXYPROLINE-RICH PROTEINS PRR12, PRAP1, SGTA PYGB 1624/4885GAA 360/4885CA12 3036/4885
US-20230256080-A1 VACCINE AND THERAPEUTIC COMPOSITIONS COMPRISING ANTIGEN-CONJUGATED VIRAL CAPSIDS TP53, LY96, BLK PYGB 4436/4885GAA 851/4885CA12 1005/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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