Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053025 | 0.87 | HRH3 (0.32) | HRH3SLC18A3 | |
| SCHEMBL7048921 | 0.78 | HRH3 (0.33) | HRH3 | |
| SCHEMBL6485374 | 0.73 | — | — | |
| SCHEMBL7053581 | 0.71 | SLC18A3 (0.34) | HRH3SLC18A3 | |
| SCHEMBL13406457 | 0.70 | HRH3 (0.42) | HRH3 | |
| SCHEMBL7053390 | 0.69 | SIGMAR1 (0.42) | SLC18A3 | |
| SCHEMBL7055902 | 0.68 | SLC18A3 (0.32) | SLC18A3 | |
| SCHEMBL7054478 | 0.68 | SIGMAR1 (0.38) | SLC18A3 | |
| SCHEMBL7055404 | 0.67 | MEN1 (0.37) | SLC18A3 | |
| SCHEMBL1428236 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030171361-A1 | Pyrrolopyrimidinone derivatives, process of preparation and use | SK CHEMICALS CO., LTD. (KR) | 2003-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171361-A1 | Pyrrolopyrimidinone derivatives, process of preparation and use | CYP2C19, DHPS, SDHA | HRH3 4329/4885SLC18A3 4784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.