Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | DUSP10 | Q9Y6W6 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4987746 | 0.86 | KMT2A (0.40) | MAPTHTTPOLBLMNANPSR1 | |
| SCHEMBL5045978 | 0.71 | GPR84 (0.50) | MAPTHTTLMNAKMT2AMEN1 | |
| SCHEMBL2332933 | 0.66 | EPHX1 (0.50) | LMNANPSR1CYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL1218849 | 0.66 | EPHX1 (0.50) | LMNANPSR1CYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL544671 | 0.66 | EPHX1 (0.50) | LMNANPSR1CYP1A2CYP2D6SMN1; SMN2 | |
| Acetic Acid SCHEMBL27430362 | 0.65 | ALOX5 (0.46) | LMNACYP2D6 | |
| Methane SCHEMBL6241814 | 0.64 | EPHX1 (0.48) | LMNANPSR1CYP1A2CYP2D6SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1137431 | 0.64 | EPHX1 (0.48) | LMNANPSR1ALDH1A1CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL1137441 | 0.64 | EPHX1 (0.48) | LMNANPSR1ALDH1A1CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL1137429 | 0.64 | EPHX1 (0.48) | LMNANPSR1ALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6569871-B1 | Antiinflammatory agents | SMITHKLINE BEECHAM CORPORATION | 2003-05-27 | — | — | US | disclosed |
| US-20030069243-A1 | Novel substituted imidazole compounds | SMITHKLINE BEECHAM CORPORATION | 2003-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069243-A1 | Novel substituted imidazole compounds | CREBBP, MAPKAPK2, CDC42BPB | MAPT 1075/4885HTT 4825/4885POLB 2053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.