SCHEMBL7049459

SCHEMBL7049459

O=C(Oc1c(Cl)cccc1Cl)c1c2ccccc2nc2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.47
MAPT P10636 6/20 0.44
HTT P42858 1/20 0.44
MEN1 O00255 2/20 0.43
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
KDM4E B2RXH2 1/20 0.42
CLK1 P49759 1/20 0.42
CDK9 P50750 1/20 0.42
CDK5 Q00535 1/20 0.42
DYRK1A Q13627 1/20 0.42
DYRK2 Q92630 1/20 0.42
CLK4 Q9HAZ1 1/20 0.42
DYRK1B Q9Y463 1/20 0.42
TSPO P30536 2/20 0.41
PTK2B Q14289 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
PDE10A Q9Y233 1/20 0.41
LMNA P02545 1/20 0.40
POLB P06746 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7045178 0.90 KMT2A (0.48) KMT2AMAPTHTTMEN1KDM4E
SCHEMBL7050016 0.88 MAOA (0.44) KMT2AMAPTHTTMEN1MAOA
SCHEMBL7049502 0.88 KDM4E (0.43) KMT2AMAPTHTTMEN1MAOA
SCHEMBL7050407 0.85 GRM2 (0.48) KMT2AMAPTHTTMEN1MAOA
SCHEMBL7755746 0.81 MAOA (0.43) KMT2AMAPTHTTMEN1MAOA
SCHEMBL38661829 0.81 MEN1 (0.49) KMT2AMAPTHTTMEN1KDM4E
SCHEMBL1054774 0.81 MEN1 (0.49) KMT2AMAPTHTTMEN1KDM4E
SCHEMBL7795326 0.81 KMT2A (0.44) KMT2AMAPTHTTMEN1KDM4E
SCHEMBL1603232 0.81 KMT2A (0.42) KMT2AMAPTHTTMEN1KDM4E
SCHEMBL7047710 0.80 MAPT (0.45) KMT2AMAPTHTTMEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0609885-B1 Acridinium compounds and conjugates thereof MOCHIDA PHARM CO LTD (JP) 2003-04-16 EP disclosed
US-5594112-A CHEMILUMINESCENCE LABEL MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1997-01-14 US disclosed
US-5438139-A Chemiluminescent; useful as immunolochemical, DNA probe and receptor bininding assays MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1995-08-01 US disclosed
EP-0609885-A1 Acridinium compounds and conjugates thereof MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1994-08-10 EP disclosed