Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TACR3 | P29371 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6584296 | 0.88 | KMT2A (0.40) | KMT2AMEN1PDE10APOLBTACR3 | |
| SCHEMBL7047504 | 0.88 | KMT2A (0.47) | KMT2AMEN1POLBTACR3MAPT | |
| SCHEMBL7787062 | 0.86 | DYRK1A (0.51) | KMT2AMEN1POLBTACR3LMNA | |
| SCHEMBL4421304 | 0.81 | KMT2A (0.50) | KMT2AMEN1PDE10APOLBLMNA | |
| SCHEMBL38661829 | 0.81 | MEN1 (0.49) | KMT2AMEN1PDE10APOLBLMNA | |
| SCHEMBL7049459 | 0.81 | KMT2A (0.47) | KMT2AMEN1PDE10APOLBLMNA | |
| SCHEMBL1054774 | 0.81 | MEN1 (0.49) | KMT2AMEN1PDE10APOLBLMNA | |
| SCHEMBL1603232 | 0.81 | KMT2A (0.42) | KMT2AMEN1PDE10APOLBLMNA | |
| SCHEMBL1602466 | 0.81 | BACE1 (0.41) | KMT2AMEN1PDE10APOLBMAPT | |
| SCHEMBL7050407 | 0.80 | GRM2 (0.48) | KMT2AMEN1PDE10APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0750748-B1 | NOVEL ARYL N-ALKYLACRIDANCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION | LUMIGEN INC (US) | 2001-12-05 | — | — | EP | disclosed |
| US-5750698-A | USEFUL IN DETECTING BOTH PEROXIDASE AND PEROXIDE | LUMIGEN, INC. (US) | 1998-05-12 | — | — | US | disclosed |
| US-5593845-A | BY REACTION WITH PEROXIDES AND PEROXIDASE; DETECTION OF HAPTENS, PROTEINS, ANTIBODIES IN ENZYME IMMUNOASSAY | LUMIGEN, INC. (US) | 1997-01-14 | — | — | US | disclosed |