SCHEMBL7049801

SCHEMBL7049801

Cc1cc(Cl)cc(Cl)c1OC(=O)C1c2ccccc2N(CC(=O)OS(=O)(=O)C(F)(F)F)c2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 1/20 0.34
ACLY P53396 2/20 0.32
LMNA P02545 2/20 0.32
MAPT P10636 2/20 0.32
HTT P42858 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
ALDH1A1 P00352 2/20 0.31
HPGD P15428 2/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
KDM4E B2RXH2 2/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
PYGL P06737 2/20 0.30
PYGM P11217 2/20 0.30
USP2 O75604 1/20 0.30
POLB P06746 1/20 0.30
ALOX15 P16050 1/20 0.30
TSHR P16473 1/20 0.30
ALOX12 P18054 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7049410 0.95 MEN1 (0.34) MAPTALDH1A1HPGDL3MBTL1MEN1
SCHEMBL7048366 0.94 ACLY (0.33) ACLY
SCHEMBL7047676 0.89 MEN1 (0.38) MAPTALDH1A1HPGDL3MBTL1MEN1
SCHEMBL7049677 0.87 FFAR2 (0.30)
SCHEMBL7046746 0.86 MEN1 (0.34) MAPTALDH1A1HPGDL3MBTL1MEN1
SCHEMBL7046990 0.86 KMT2A (0.33) ALDH1A1HPGDL3MBTL1MEN1KMT2A
SCHEMBL7049435 0.85 ALDH1A1 (0.35) MAPTALDH1A1HPGDL3MBTL1MEN1
SCHEMBL7046766 0.84
SCHEMBL7050778 0.83 PPARG (0.33) MAPTALDH1A1HPGDKDM4EMEN1
SCHEMBL7047551 0.82 PPARG (0.37) MAPTALDH1A1HPGDL3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0609885-B1 Acridinium compounds and conjugates thereof MOCHIDA PHARM CO LTD (JP) 2003-04-16 EP disclosed
US-5594112-A CHEMILUMINESCENCE LABEL MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1997-01-14 US disclosed
US-5438139-A Chemiluminescent; useful as immunolochemical, DNA probe and receptor bininding assays MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1995-08-01 US disclosed
EP-0609885-A1 Acridinium compounds and conjugates thereof MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1994-08-10 EP disclosed