Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL284729 | 0.82 | TDP1 (0.73) | MAPTTDP1ALDH1A1POLBKDM4E | |
| SCHEMBL28865485 | 0.77 | CES2 (0.56) | MAPTRECQLALDH1A1POLBCES2 | |
| SCHEMBL29843413 | 0.77 | CES2 (0.65) | MAPTRECQLALDH1A1POLBCES2 | |
| SCHEMBL263770 | 0.77 | CES2 (0.65) | MAPTRECQLALDH1A1POLBCES2 | |
| SCHEMBL5693922 | 0.76 | TDP1 (0.63) | MAPTTDP1RECQLMAPK14ALDH1A1 | |
| Benzamide SCHEMBL9171626 | 0.76 | POLB (0.64) | MAPTTDP1RECQLALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL4373213 | 0.75 | CES2 (0.62) | MAPTRECQLALDH1A1POLBCES2 | |
| SCHEMBL4873515 | 0.75 | CES2 (0.62) | MAPTRECQLALDH1A1POLBCES2 | |
| Hydrochloric Acid SCHEMBL404721 | 0.75 | CES2 (0.62) | MAPTRECQLALDH1A1POLBCES2 | |
| Acetic Acid SCHEMBL29291113 | 0.73 | ALDH1A1 (0.59) | MAPTALDH1A1POLBCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303574-A1 | AMIDE-BASED ANTIFREEZE CONCENTRATES AND COOLANT COMPOSITIONS CONTAINING THE SAME FOR PROTECTING MAGNESIUM AND MAGNESIUM ALLOYS | BASF AKTIENGESELLSCHAFT (DE) | 2003-04-23 | — | — | EP | disclosed |
| WO-2002008354-A1 | AMIDE-BASED ANTIFREEZE CONCENTRATES AND COOLANT COMPOSITIONS CONTAINING THE SAME FOR PROTECTING MAGNESIUM AND MAGNESIUM ALLOYS | BASF AKTIENGESELLSCHAFT (DE) | 2002-01-31 | — | — | WO | disclosed |