Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 8/20 | 0.39 |
| ▸ | CTSS | P25774 | 7/20 | 0.39 |
| ▸ | CTSB | P07858 | 5/20 | 0.39 |
| ▸ | CTSK | P43235 | 4/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9915100 | 0.83 | TSHR (0.48) | TSHRSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL4007778 | 0.83 | MAOB (0.39) | CTSLCTSSCTSBCTSKMAOB | |
| SCHEMBL4007775 | 0.83 | MAOB (0.39) | CTSLCTSSCTSBCTSKMAOB | |
| SCHEMBL14133152 | 0.82 | CTSL (0.44) | CTSLCTSSCTSBCTSKMAOB | |
| SCHEMBL28093718 | 0.81 | CTSL (0.36) | CTSLCTSSCTSBCTSKMAOB | |
| SCHEMBL28093698 | 0.81 | CTSL (0.38) | CTSLCTSSCTSBCTSKMAOB | |
| SCHEMBL9522728 | 0.79 | MAOB (0.44) | CTSLCTSSCTSBCTSKMAOB | |
| SCHEMBL9716292 | 0.78 | TLR2 (0.41) | CTSLCTSS | |
| SCHEMBL2354398 | 0.78 | MAOB (0.43) | CTSLCTSSCTSBCTSKMAOB | |
| SCHEMBL28328694 | 0.78 | TRPA1 (0.44) | CTSLCTSBCTSKTSHRSLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305280-A2 | PROCESS FOR MAKING 3-HYDROXYALKANENITRILES AND HYDROXYAMINOALKANES | E. I. du Pont de Nemours and Company (US) | 2003-05-02 | — | — | EP | disclosed |
| US-6384263-B1 | Process for making 3-hydroxyalkanelnitriles and conversion of the 3-hydroxyalkanelnitrile to an hydroxyaminoalkane | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-05-07 | — | — | US | disclosed |
| US-20020022737-A1 | Process for making 3-hydroxyalkanelnitriles and conversion of the 3-hydroxyalkanelnitrile to an hydroxyaminoalkane | INV NYLON CHEMICALS AMERICAS, LLC | 2002-02-21 | — | — | US | disclosed |
| WO-2002012173-A2 | PROCESS FOR MAKING 3-HYDROXYALKANENITRILES AND HYDROXYAMINOALKANES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-02-14 | — | — | WO | disclosed |