SCHEMBL7050459

SCHEMBL7050459

FN(C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17092892 1.00 LMNA (0.36) LMNATHRB
SCHEMBL7050738 1.00 LMNA (0.36) LMNATHRB
SCHEMBL6408306 0.88
SCHEMBL9903892 0.88 LMNA (0.40) LMNATHRB
SCHEMBL345872 0.88 LMNA (0.40) LMNATHRB
SCHEMBL9903342 0.85 LMNA (0.38) LMNATHRB
SCHEMBL3657606 0.85 LMNA (0.38) LMNATHRB
SCHEMBL9686592 0.85 LMNA (0.38) LMNATHRB
SCHEMBL5453225 0.84 LMNA (0.35) LMNA
SCHEMBL28581071 0.82 LMNA (0.36) LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0845058-B1 FIBROUS WEBS HAVING ENHANCED ELECTRET PROPERTIES MINNESOTA MINING & MFG (US) 2003-04-23 EP disclosed
US-6268495-B1 POLYAMINETRIAZINE COMPOUNDS 3M INNOVATIVE PROPERTIES COMPANY 2001-07-31 US disclosed
US-5976208-A FIBROUS WEB OF A BLEND OF A THERMOPLASTIC RESIN AND AT LEAST ONE COMPOUND OR OLIGOMER THAT ENHANCES THE WEB'S ELECTRET PROPERTIES. MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-11-02 US disclosed
US-5968635-A BLEND OF A THERMOPLASTIC RESIN AND AN IMIDE COMPOUND OR OLIGOMER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-10-19 US disclosed
US-5919847-A BLEND OF THERMOPLASTIC RESIN AND ADDITIVE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-07-06 US disclosed
US-5908598-A Fibrous webs having enhanced electret properties MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-06-01 US disclosed
EP-0845058-A1 FIBROUS WEBS HAVING ENHANCED ELECTRET PROPERTIES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-06-03 EP disclosed
WO-1997007272-A1 FIBROUS WEBS HAVING ENHANCED ELECTRET PROPERTIES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-02-27 WO disclosed