SCHEMBL705065

SCHEMBL705065

CCCCCC[Si](C)(OC(C)(C)C)C1c2ccccc2-c2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.38
BCHE P06276 1/20 0.38
CHRM2 P08172 1/20 0.33
HTR1A P08908 1/20 0.33
ADRA2A P08913 1/20 0.33
CHRM1 P11229 1/20 0.33
DRD1 P21728 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
ADRA1A P35348 1/20 0.33
OPRM1 P35372 1/20 0.33
DRD3 P35462 1/20 0.33
SLC6A3 Q01959 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7576879 0.77 ACHE (0.45) ACHEBCHECHRM2HTR1AADRA2A
SCHEMBL2339323 0.77 ACHE (0.45) ACHEBCHECHRM2HTR1AADRA2A
SCHEMBL28301540 0.72 ACHE (0.42) ACHEBCHECHRM2HTR1AADRA2A
SCHEMBL4034020 0.71 ACHE (0.47) ACHEBCHECHRM2HTR1AADRA2A
SCHEMBL18122238 0.70 CHRM2 (0.33) ACHECHRM2HTR1AADRA2ACHRM1
SCHEMBL6736293 0.70 CHRM2 (0.33) ACHECHRM2HTR1AADRA2ACHRM1
SCHEMBL7197597 0.69 ACHE (0.49) ACHEBCHECHRM2HTR1AADRA2A
SCHEMBL18122305 0.69 POLB (0.32) ACHEBCHECHRM2HTR1AADRA2A
SCHEMBL17697954 0.69 ACHE (0.32) ACHEBCHECHRM2HTR1AADRA2A
SCHEMBL19901170 0.66 CHRM2 (0.30) ACHECHRM2HTR1AADRA2ACHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1910207-B Supported metallocene catalyst, method of preparing the catalyst and method of preparing polyolefin using the catalyst LG ELECTRONICS INC 2013-03-27 CN disclosed
EP-2423204-A1 THIAZOLIDINONE DERIVATIVE SBI Biotech Co., Ltd. (JP) 2012-02-29 EP disclosed
CN-1910207-A Supported metallocene catalyst, method of preparing the catalyst and method of preparing polyolefin using the catalyst LG CHEMICAL LTD (KR) 2007-02-07 CN disclosed