SCHEMBL6736293

SCHEMBL6736293

CC(C)(C)OCCCCCC[Si](C)(C1c2ccccc2-c2ccccc21)C1c2ccccc2-c2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.33
HTR1A P08908 1/20 0.33
ADRA2A P08913 1/20 0.33
CHRM1 P11229 1/20 0.33
DRD1 P21728 1/20 0.33
ACHE P22303 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
ADRA1A P35348 1/20 0.33
OPRM1 P35372 1/20 0.33
DRD3 P35462 1/20 0.33
SLC6A3 Q01959 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18122238 1.00 CHRM2 (0.33) CHRM2HTR1AADRA2ACHRM1DRD1
SCHEMBL18122305 0.99 POLB (0.32) CHRM2HTR1AADRA2ACHRM1DRD1
SCHEMBL19901170 0.91 CHRM2 (0.30) CHRM2HTR1AADRA2ACHRM1DRD1
SCHEMBL18594521 0.89 IDO1 (0.31)
SCHEMBL15497874 0.88 POLB (0.33) CHRM2HTR1AADRA2ACHRM1DRD1
SCHEMBL18760055 0.86 PDK2 (0.31)
SCHEMBL17697954 0.86 ACHE (0.32) CHRM2HTR1AADRA2ACHRM1DRD1
SCHEMBL19451455 0.84 RARA (0.32)
SCHEMBL19901169 0.84 PPARG (0.31)
SCHEMBL18594529 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240026041-A1 Polyethylene and Preparation Method Thereof LG CHEM, LTD. (KR) 2024-01-25 US disclosed
US-20240018283-A1 ORGANIC-INORGANIC HYBRID POLYOLEFIN COMPOSITE AND PREPARATION METHOD THEREOF LG CHEM, LTD. (KR) 2024-01-18 US disclosed
US-11702488-B2 Polyethylene and chlorinated polyethylene thereof LG CHEM, LTD. 2023-07-18 US disclosed
US-9963527-B2 Transition metal compound, catalyst composition comprising the same, and method of preparing polyolefin LG CHEM, LTD. (KR) 2018-05-08 US disclosed
US-9963527-B2 Transition metal compound, catalyst composition comprising the same, and method of preparing polyolefin LG CHEM, LTD. (KR) 2018-05-08 US disclosed
US-9926395-B2 Hybrid supported metallocene catalyst LG CHEM, LTD. (KR) 2018-03-27 US disclosed
US-9902789-B2 Method for preparing hybrid supported metallocene catalyst LG CHEM, LTD. (KR) 2018-02-27 US disclosed
US-20170198074-A1 TRANSITION METAL COMPOUND, CATALYST COMPOSITION COMPRISING THE SAME, AND METHOD OF PREPARING POLYOLEFIN LG CHEM, LTD. (KR) 2017-07-13 US disclosed
US-20170198074-A1 TRANSITION METAL COMPOUND, CATALYST COMPOSITION COMPRISING THE SAME, AND METHOD OF PREPARING POLYOLEFIN LG CHEM, LTD. (KR) 2017-07-13 US disclosed
US-9644064-B2 Olefin block copolymer LG CHEM, LTD. (KR) 2017-05-09 US disclosed
US-9000115-B2 Olefin block copolymers and production methods thereof LG CHEM, LTD. (KR) 2015-04-07 US disclosed
US-9000115-B2 Olefin block copolymers and production methods thereof LG CHEM, LTD. (KR) 2015-04-07 US disclosed
US-20140114033-A1 OLEFIN BLOCK COPOLYMERS AND PRODUCTION METHODS THEREOF LG CHEM, LTD. (KR) 2014-04-24 US disclosed
US-20140066288-A1 METALLOCENE COMPOUND, CATALYST COMPOSITION COMPRISING THE SAME, AND AN OLEFINIC POLYMER PRODUCED USING THE SAME LG CHEM, LTD. (KR) 2014-03-06 US disclosed
US-20130296519-A1 OLEFIN BLOCK COPOLYMER LG CHEM, LTD. (KR) 2013-11-07 US disclosed
US-20130296497-A1 OLEFIN BLOCK COPOLYMER LG CHEM, LTD. (KR) 2013-11-07 US disclosed
US-20130296497-A1 OLEFIN BLOCK COPOLYMER LG CHEM, LTD. (KR) 2013-11-07 US disclosed
US-20130296519-A1 OLEFIN BLOCK COPOLYMER LG CHEM, LTD. (KR) 2013-11-07 US disclosed
US-20120196985-A1 OLEFIN BLOCK COPOLYMERS AND PRODUCTION METHODS THEREOF LG CHEM, LTD. (KR) 2012-08-02 US disclosed
US-20120123078-A1 METALLOCENE COMPOUND, CATALYST COMPOSITION COMPRISING THE SAME, AND AN OLEFINIC POLYMER PRODUCED USING THE SAME LG CHEM, LTD. (KR) 2012-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120123078-A1 METALLOCENE COMPOUND, CATALYST COMPOSITION COMPRISING THE SAME, AND AN OLEFINIC POLYMER PRODUCED USING THE SAME NOTUM, OR10J3, COASY CHRM2 3891/4885HTR1A 3559/4885ADRA2A 4275/4885
US-20170198074-A1 TRANSITION METAL COMPOUND, CATALYST COMPOSITION COMPRISING THE SAME, AND METHOD OF PREPARING POLYOLEFIN PARG, TRMT1L, PORCN CHRM2 4226/4885HTR1A 4741/4885ADRA2A 4876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.