Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7114435 | 0.92 | AR (0.43) | HTR2AMAPTKDM4EALDH1A1CETP | |
| SCHEMBL6052468 | 0.88 | TRPV4 (0.46) | POLBSMOMAPTKDM4EALDH1A1 | |
| SCHEMBL7057633 | 0.86 | ALDH1A1 (0.42) | HTR2AMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL7057696 | 0.85 | MAPT (0.40) | HTR2AMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL7056356 | 0.85 | DRD4 (0.46) | HTR2AMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL7057735 | 0.85 | MAPT (0.41) | HTR2APOLBMAPTKDM4EALDH1A1 | |
| SCHEMBL7059077 | 0.85 | ALDH1A1 (0.41) | HTR2AMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL7058704 | 0.84 | MAPT (0.39) | HTR2AMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL7062059 | 0.83 | DRD4 (0.40) | HTR2AMAPTALDH1A1LMNADRD4 | |
| SCHEMBL7055974 | 0.82 | DRD2 (0.42) | HTR2AMAPTKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1176140-B1 | AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2004-12-29 | — | — | EP | claimed |