Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6052213 | 0.86 | ALDH1A1 (0.45) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL7055222 | 0.84 | ALDH1A1 (0.41) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL7055402 | 0.84 | MEN1 (0.42) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL7058704 | 0.83 | MAPT (0.39) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL7057806 | 0.81 | ALDH1A1 (0.43) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL7055974 | 0.80 | DRD2 (0.42) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL6052307 | 0.79 | MAPT (0.46) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL7062059 | 0.79 | DRD4 (0.40) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL6052359 | 0.78 | RXFP1 (0.48) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL7058149 | 0.78 | XDH (0.47) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1176140-B1 | AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2004-12-29 | — | — | EP | claimed |