Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.47 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7419755 | 1.00 | ABCB11 (0.70) | ABCB11ALDH1A1GAAMAPTTSHR | |
| SCHEMBL6680649 | 0.84 | ABCB11 (0.56) | ABCB11ALDH1A1GAAMAPTTSHR | |
| SCHEMBL11705595 | 0.83 | ABCB11 (0.51) | ABCB11ALDH1A1GAAMAPTTSHR | |
| SCHEMBL2641075 | 0.83 | ABCB11 (0.52) | ABCB11TSHRCYP2C9ACHETDP1 | |
| Naproxol SCHEMBL29979997 | 0.83 | ABCB11 (1.00) | ABCB11MAPTTSHRCYP2C9L3MBTL1 | |
| Naproxol SCHEMBL30599771 | 0.83 | ABCB11 (1.00) | ABCB11MAPTTSHRCYP2C9L3MBTL1 | |
| Naproxol SCHEMBL43203 | 0.83 | ABCB11 (1.00) | ABCB11MAPTTSHRCYP2C9L3MBTL1 | |
| Naproxol SCHEMBL10395753 | 0.83 | ABCB11 (1.00) | ABCB11MAPTTSHRCYP2C9L3MBTL1 | |
| Naproxol SCHEMBL8471214 | 0.83 | ABCB11 (1.00) | ABCB11MAPTTSHRCYP2C9L3MBTL1 | |
| SCHEMBL4454111 | 0.82 | CA1 (0.52) | ABCB11ALDH1A1GAAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118955244-A | Method for preparing primary alcohol by homogeneously catalyzing and reducing carboxylic acid derivative by using N-heterocyclic carbene copper complex | 延安大学 | 2024-11-15 | — | — | CN | disclosed |
| EP-3365334-B1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2024-07-17 | — | — | EP | disclosed |
| CN-117751155-A | Copolymerization of aldehydes and vinyl ethers | 巴斯夫欧洲公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-117440986-A | Polyisobutene having a high content of specific double bond isomers | 巴斯夫欧洲公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-113698514-B | Process for preparing highly reactive isobutylene homo-or copolymers | 巴斯夫欧洲公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-116075531-A | Process for preparing highly reactive isobutylene homo-or copolymers | 巴斯夫欧洲公司 | 2023-05-05 | — | — | CN | disclosed |
| US-20230019032-A1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2023-01-19 | — | — | US | disclosed |
| CN-108602913-B | Method for producing highly reactive isobutene homo-or copolymers | 巴斯夫欧洲公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-113698514-A | Method for producing highly reactive isobutene homo-or copolymers | 巴斯夫欧洲公司 | 2021-11-26 | — | — | CN | disclosed |
| CN-109415452-B | Method for producing highly reactive isobutene homo-or copolymers | 巴斯夫欧洲公司 | 2021-10-26 | — | — | CN | disclosed |
| CN-110997737-A | Method for producing highly reactive isobutene homo-or copolymers | 巴斯夫欧洲公司 | 2020-04-10 | — | — | CN | disclosed |
| US-10457669-B2 | Benzolactam compounds as protein kinase inhibitors | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2019-10-29 | — | — | US | disclosed |
| CN-109415452-A | The method for preparing highly reactive isobutylene homo or copolymer | 巴斯夫欧洲公司 | 2019-03-01 | — | — | CN | disclosed |
| US-20190047990-A1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2019-02-14 | — | — | US | disclosed |
| CN-108602913-A | The method for preparing highly reactive isobutylene homo or copolymer | 巴斯夫欧洲公司 | 2018-09-28 | — | — | CN | disclosed |
| CN-108602914-A | Method for producing highly reactive isobutene homo-or copolymers | 巴斯夫欧洲公司 | 2018-09-28 | — | — | CN | disclosed |
| EP-0882715-B1 | NOVEL N-(UNSUBSTITUTED OR SUBSTITUTED)-4-SUBSTITUTED-6-(UNSUBSTITUTED OR SUBSTITUTED)PHENOXY-2-PYRIDINECARBOXAMIDES OR THIOCARBOXAMIDES, PROCESSES FOR PRODUCING THE SAME, AND HERBICIDES | KUREHA CHEMICAL IND CO LTD (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6339045-B1 | CAN BE USED IN A SMALL AMOUNT, SHOWING A GOOD SELECTIVITY BETWEEN CROP AND WEED, AND CAUSING NO PHYTOTOXICITY | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2002-01-15 | — | — | US | disclosed |
| EP-0882715-A1 | NOVEL N-(UNSUBSTITUTED OR SUBSTITUTED)-4-SUBSTITUTED-6-(UNSUBSTITUTED OR SUBSTITUTED)PHENOXY-2-PYRIDINECARBOXAMIDES OR THIOCARBOXAMIDES, PROCESSES FOR PRODUCING THE SAME, AND HERBICIDES | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-12-09 | — | — | EP | disclosed |
| US-4151179-A | ANTIINFLAMMATORY AGENTS | FISONS LIMITED (GB) | 1979-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230019032-A1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | MAPK1, ALK, MAP3K1 | ABCB11 2337/4885ALDH1A1 1598/4885GAA 4612/4885 |
| US-20190047990-A1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | MAPK1, ALK, MAP3K1 | ABCB11 2337/4885ALDH1A1 1598/4885GAA 4612/4885 |
| US-10457669-B2 | Benzolactam compounds as protein kinase inhibitors | MAPK1, ALK, MAP3K1 | ABCB11 2337/4885ALDH1A1 1598/4885GAA 4612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.