Sugi Predict

Sugi Predict / Compounds / SCHEMBL7051704

SCHEMBL7051704

SCHEMBL7051704

CC(C)CN(C(CCSCc1ccccc1)C(=O)NO)S(=O)(=O)c1ccc(-c2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ MMP3 P08254 18/20 1.00
▸ MMP2 P08253 18/20 1.00
▸ MMP9 P14780 18/20 1.00
▸ MMP13 P45452 16/20 1.00
▸ MMP1 P03956 10/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8041515 0.93 MMP3 (0.86) MMP3MMP2MMP9MMP13MMP1
SCHEMBL7055373 0.92 MMP3 (1.00) MMP3MMP2MMP9MMP13MMP1
SCHEMBL7053227 0.90 MMP3 (0.81) MMP3MMP2MMP9MMP13MMP1
SCHEMBL9247824 0.90 MMP3 (0.90) MMP3MMP2MMP9MMP13MMP1
SCHEMBL7053893 0.90 MMP3 (0.90) MMP3MMP2MMP9MMP13MMP1
SCHEMBL8029542 0.88 MMP3 (0.79) MMP3MMP2MMP9MMP13MMP1
SCHEMBL8046605 0.88 MMP3 (0.78) MMP3MMP2MMP9MMP13MMP1
SCHEMBL7054085 0.88 MMP2 (1.00) MMP3MMP2MMP9MMP13MMP1
SCHEMBL7050690 0.84 MMP3 (1.00) MMP3MMP2MMP9MMP13MMP1
SCHEMBL7056498 0.82 MMP3 (0.83) MMP3MMP2MMP9MMP13MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0979816-B1 Hydroxamic acid derivatives, process for their preparation and pharmaceutical compositions containing them SERVIER LAB (FR) 2003-05-02 — — EP claimed
US-6063816-A Hydroxamic acid compounds ADIR ET COMPAGNIE (FR) 2000-05-16 — — US claimed