Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 18/20 | 1.00 |
| ▸ | MMP9 | P14780 | 18/20 | 1.00 |
| ▸ | MMP3 | P08254 | 12/20 | 1.00 |
| ▸ | MMP13 | P45452 | 11/20 | 1.00 |
| ▸ | MMP1 | P03956 | 10/20 | 1.00 |
| ▸ | MMP14 | P50281 | 8/20 | 0.55 |
| ▸ | MMP8 | P22894 | 2/20 | 0.55 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053943 | 0.89 | MMP2 (0.80) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL7051704 | 0.88 | MMP3 (1.00) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL8039450 | 0.87 | MMP9 (0.77) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL8041515 | 0.83 | MMP3 (0.86) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL7055373 | 0.82 | MMP3 (1.00) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL8043065 | 0.80 | MMP2 (0.66) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL1771031 | 0.78 | MMP13 (0.64) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL1770554 | 0.78 | MMP13 (0.64) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL9247824 | 0.77 | MMP3 (0.90) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL7053893 | 0.77 | MMP3 (0.90) | MMP2MMP9MMP3MMP13MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979816-B1 | Hydroxamic acid derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-05-02 | — | — | EP | claimed |
| US-6063816-A | Hydroxamic acid compounds | ADIR ET COMPAGNIE (FR) | 2000-05-16 | — | — | US | claimed |
| US-6063816-A | Hydroxamic acid compounds | ADIR ET COMPAGNIE (FR) | 2000-05-16 | — | — | US | disclosed |