Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.72 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.72 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7051749 | 1.00 | AGTR1 (0.72) | AGTR1ABCC3ABCC2 | |
| SCHEMBL9452752 | 0.91 | AGTR1 (0.61) | AGTR1ABCC3ABCC2 | |
| SCHEMBL7051753 | 0.89 | AGTR1 (0.77) | AGTR1ABCC3ABCC2 | |
| SCHEMBL7446920 | 0.89 | AGTR1 (0.77) | AGTR1ABCC3ABCC2 | |
| SCHEMBL682668 | 0.87 | AGTR1 (0.75) | AGTR1ABCC3ABCC2 | |
| SCHEMBL9125136 | 0.87 | AGTR1 (0.85) | AGTR1ABCC3ABCC2 | |
| SCHEMBL9575033 | 0.86 | AGTR1 (0.65) | AGTR1ABCC3ABCC2 | |
| SCHEMBL9575039 | 0.86 | AGTR1 (0.65) | AGTR1ABCC3ABCC2 | |
| SCHEMBL9424461 | 0.85 | AGTR1 (0.72) | AGTR1ABCC3ABCC2 | |
| SCHEMBL9424465 | 0.85 | AGTR1 (0.72) | AGTR1ABCC3ABCC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030187044-A1 | Medicament | SMITHKLINE BEECHAM P.L.C. | 2003-10-02 | — | — | US | claimed |
| US-20030096851-A1 | Medicament | SMITHKLINE BEECHAM P.L.C. | 2003-05-22 | — | — | US | claimed |
| US-20030069293-A1 | Medicament | SMITHKLINE BEECHAM PLC | 2003-04-10 | — | — | US | claimed |
| US-20030050285-A1 | Substituted imidazoles; angiotensin II receptor antagonist for the treatment of hemorrhagic stroke | SMITHKLINE BEECHAM P.L.C. | 2003-03-13 | — | — | US | claimed |
| US-20030004201-A1 | Medicament | SMITHKLINE BEECHAM P.L.C. | 2003-01-02 | — | — | US | claimed |
| US-20020160985-A1 | Medicament | SMITHKLINE BEECHAM PLC | 2002-10-31 | — | — | US | claimed |
| US-20020132840-A1 | Treating angina in a mammal by administering an angiotensin II receptor antagonist. | SMITHKLINE BEECHAM P.1.C. | 2002-09-19 | — | — | US | claimed |
| US-20020128300-A1 | Treating diabetic retinopathy in a mammal by administering an angiotensin II receptor antagonist. | SMITHKLINE BEECHAM P.L.C. | 2002-09-12 | — | — | US | claimed |
| US-20020086893-A1 | Imidazole based angiotensin II receptor antagonist for treating haemorrhagic stroke | SMITHKLINE BEECHAM P.L.C. | 2002-07-04 | — | — | US | claimed |
| US-20020068759-A1 | Medicament | SMITHKLINE BEECHAM PLC | 2002-06-06 | — | — | US | claimed |
| WO-1992010186-A1 | USE OF ANGIOTENSN II RECEPTOR ANTAGONISTS FOR THE PREPARATION OF A MEDICAMENT FOR IMPROVING COGNITIVE FUNCTION | SMITHKLINE BEECHAM PLC (GB) | 1992-06-25 | — | — | WO | claimed |
| WO-1992010184-A1 | USE OF ANGIOTENSIN II RECEPTOR ANTAGONISTS IN THE TREATMENT OF ATHEROMA | SMITHKLINE BEECHAM PLC (GB) | 1992-06-25 | — | — | WO | claimed |
| WO-1992010183-A1 | USE OF ANGIOTENSIN II RECEPTOR ANTAGONISTS IN THE TREATMENT OF DIABETIC RETINOPATHY | SMITHKLINE BEECHAM PLC (GB) | 1992-06-25 | — | — | WO | claimed |
| WO-1992010185-A1 | USE OF ANGIOTENSIN II RECEPTOR ANTAGONISTS IN THE PREVENTION OF RESTINOSIS | SMITHKLINE BEECHAM PLC (GB) | 1992-06-25 | — | — | WO | claimed |
| WO-1992010180-A1 | USE OF ANGIOTENSIN II ANTAGONIST IN THE TREATMENT OF INFARCTION | SMITHKLINE BEECHAM PLC (GB) | 1992-06-25 | — | — | WO | claimed |
| WO-1992010188-A1 | USE OF ANGIOTENSIN II RECEPTOR ANTAGONISTS IN THE TREATMENT OF HEMORRAGIC STROKE | SMITHKLINE BEECHAM PLC (GB) | 1992-06-25 | — | — | WO | claimed |
| WO-1992010181-A1 | USE OF ANGIOTENSIN II ANTAGONISTS IN THE TREATMENT OF LEFT VENTRICULAR HYPERTROPHY | SMITHKLINE BEECHAM PLC (GB) | 1992-06-25 | — | — | WO | claimed |
| WO-1992010182-A1 | USE OF ANGIOTENSIN II RECEPTOR ANTAGONISTS IN THE TREATMENT OF DIABETIC NEPHROPATHY | SMITHKLINE BEECHAM PLC (GB) | 1992-06-25 | — | — | WO | claimed |
| WO-1992010179-A1 | USE OF ANGIOTENSIN II RECEPTOR ANTAGONISTS IN THE TREATMENT OF MACULAR DEGENERATION | SMITHKLINE BEECHAM PLC (GB) | 1992-06-25 | — | — | WO | claimed |
| WO-1992010187-A1 | USE OF ANGIOTENSIN II ANTAGONISTS IN THE TREATMENT OF ANGINA PECTORIS | SMITHKLINE BEECHAM PLC (GB) | 1992-06-25 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020160985-A1 | Medicament | AGTR2, AGTR1, ACE | AGTR1 2/4885ABCC3 808/4885ABCC2 577/4885 |
| US-20020132840-A1 | Treating angina in a mammal by administering an angiotensin II receptor antagonist. | AGTR2, AGTR1, AGT | AGTR1 2/4885ABCC3 1102/4885ABCC2 523/4885 |
| US-20030187044-A1 | Medicament | AGTR2, AGTR1, ACE | AGTR1 2/4885ABCC3 2090/4885ABCC2 1339/4885 |
| US-20020086893-A1 | Imidazole based angiotensin II receptor antagonist for treating haemorrhagic stroke | AGTR2, AGTR1, VIPR2 | AGTR1 2/4885ABCC3 3754/4885ABCC2 2325/4885 |
| US-20030004201-A1 | Medicament | AGTR2, AGTR1, ACE | AGTR1 2/4885ABCC3 860/4885ABCC2 900/4885 |
| US-20020068759-A1 | Medicament | AGTR2, AGTR1, ACE | AGTR1 2/4885ABCC3 808/4885ABCC2 577/4885 |
| US-20030096851-A1 | Medicament | AGTR2, AGTR1, ACE | AGTR1 2/4885ABCC3 2090/4885ABCC2 1339/4885 |
| US-20030050285-A1 | Substituted imidazoles; angiotensin II receptor antagonist for the treatment of hemorrhagic stroke | AGTR2, AGTR1, ACE | AGTR1 2/4885ABCC3 3372/4885ABCC2 2275/4885 |
| US-20030069293-A1 | Medicament | AGTR2, AGTR1, ACE | AGTR1 2/4885ABCC3 808/4885ABCC2 577/4885 |
| US-20020128300-A1 | Treating diabetic retinopathy in a mammal by administering an angiotensin II receptor antagonist. | AGTR2, AGTR1, REN | AGTR1 2/4885ABCC3 1592/4885ABCC2 971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.