Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.51 |
| ▸ | FNTA | P49354 | 8/20 | 0.42 |
| ▸ | FNTB | P49356 | 8/20 | 0.42 |
| ▸ | PGGT1B | P53609 | 7/20 | 0.42 |
| ▸ | GRM5 | P41594 | 3/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | LDLR | P01130 | 1/20 | 0.35 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7571137 | 0.74 | KDM4E (0.49) | IDO1HPGDSLDLRPCSK9 | |
| SCHEMBL6208653 | 0.74 | TDP1 (0.52) | IDO1FNTAFNTBPGGT1BGRM5 | |
| SCHEMBL22776004 | 0.72 | — | — | |
| SCHEMBL7166244 | 0.71 | IDO1 (0.44) | IDO1HPGDS | |
| SCHEMBL2519799 | 0.70 | TSHR (0.52) | IDO1GRM5APP | |
| SCHEMBL17845069 | 0.70 | APP (0.48) | IDO1GRM5HSD17B2APP | |
| SCHEMBL2801832 | 0.70 | TSHR (0.52) | IDO1GRM5APP | |
| SCHEMBL6103627 | 0.70 | — | — | |
| SCHEMBL8189671 | 0.69 | FNTA (0.60) | FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL7570009 | 0.69 | HPGDS (0.39) | IDO1FNTAFNTBPGGT1BHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030216441-A1 | Farnesyltransferase inhibitors | WEINSTOCK, STEVEN F. | 2003-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216441-A1 | Farnesyltransferase inhibitors | FNTA, FNTB, LCAT | IDO1 4436/4885FNTA 1/4885FNTB 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.