Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 10/20 | 0.67 |
| ▸ | BACE1 | P56817 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7049163 | 0.87 | HSP90AA1 (0.67) | HSP90AA1BACE1ALDH1A1HTTRAB9A | |
| SCHEMBL7509553 | 0.86 | HSP90AA1 (0.65) | HSP90AA1BACE1ALDH1A1KMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL1194544 | 0.85 | HSP90AA1 (0.61) | HSP90AA1BACE1ALDH1A1HTT | |
| SCHEMBL7506903 | 0.83 | KMT2A (0.56) | HSP90AA1ALDH1A1LMNAKMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL1193911 | 0.82 | HSP90AA1 (0.70) | HSP90AA1BACE1ALDH1A1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL7110808 | 0.82 | HSP90AA1 (0.70) | HSP90AA1BACE1ALDH1A1LMNAKMT2A | |
| Bromide SCHEMBL7052966 | 0.82 | KMT2A (0.58) | ALDH1A1LMNAKMT2ACYP1A2ADRB2 | |
| SCHEMBL5466834 | 0.82 | HSP90AA1 (0.77) | HSP90AA1BACE1ALDH1A1LMNAHTT | |
| SCHEMBL6223892 | 0.81 | HSP90AA1 (0.68) | HSP90AA1BACE1ALDH1A1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL7048253 | 0.81 | HSP90AA1 (0.45) | HSP90AA1BACE1ALDH1A1LMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020103228-A1 | Composition and method for use of pyridinium derivatives in cosmetic and therapeutic applications | TORRENT PHARMACEUTICALS LTD. | 2002-08-01 | — | — | US | claimed |
| EP-1304101-A1 | Composition and method for use of pyridinium derivatives in cosmetic and therapeutic applications | Torrent Pharmaceuticals Ltd (IN) | 2003-04-23 | — | — | EP | disclosed |
| US-20020103228-A1 | Composition and method for use of pyridinium derivatives in cosmetic and therapeutic applications | TORRENT PHARMACEUTICALS LTD. | 2002-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020103228-A1 | Composition and method for use of pyridinium derivatives in cosmetic and therapeutic applications | PNPO, PRDX5, PLPBP | HSP90AA1 4863/4885BACE1 1232/4885ALDH1A1 662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.