Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 9/20 | 0.70 |
| ▸ | BACE1 | P56817 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1193911 | 1.00 | HSP90AA1 (0.70) | HSP90AA1BACE1KMT2APTGS2LMNA | |
| SCHEMBL6223892 | 0.99 | HSP90AA1 (0.68) | HSP90AA1BACE1KMT2APTGS2LMNA | |
| SCHEMBL6227213 | 0.85 | KMT2A (0.61) | HSP90AA1KMT2APTGS2LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL1194709 | 0.84 | HSP90AA1 (0.66) | HSP90AA1BACE1KMT2A | |
| Bromide SCHEMBL1194169 | 0.84 | KMT2A (0.63) | HSP90AA1KMT2APTGS2LMNAALDH1A1 | |
| SCHEMBL5466834 | 0.84 | HSP90AA1 (0.77) | HSP90AA1BACE1KMT2ALMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL1193875 | 0.83 | HSP90AA1 (0.62) | HSP90AA1BACE1KMT2ALMNA | |
| SCHEMBL6224547 | 0.83 | HSP90AA1 (0.64) | HSP90AA1BACE1KMT2A | |
| Hydrochloric Acid SCHEMBL7051973 | 0.82 | HSP90AA1 (0.67) | HSP90AA1BACE1KMT2ALMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL1193611 | 0.80 | HSP90AA1 (0.73) | HSP90AA1BACE1LMNAALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030032660-A1 | Breaking preformed AGE | TORRENT PHARMACEUTICALS LTD. | 2003-02-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030032660-A1 | Breaking preformed AGE | AGER, GPX1, RBP1 | HSP90AA1 4802/4885BACE1 76/4885KMT2A 4457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.