SCHEMBL9708959

SCHEMBL9708959

OC[C@H]1OC(O)(F)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PYGB P11216 8/20 0.43
PYGL P06737 3/20 0.43
PYGM P11217 2/20 0.43
LMNA P02545 1/20 0.36
GBA1 P04062 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2353972 1.00 PYGB (0.43) PYGBPYGLPYGMLMNAGBA1
SCHEMBL7742729 1.00 PYGB (0.43) PYGBPYGLPYGMLMNAGBA1
SCHEMBL11913232 1.00 PYGB (0.43) PYGBPYGLPYGMLMNAGBA1
SCHEMBL9751326 0.93 PYGB (0.37) PYGBPYGLPYGMLMNAGBA1
SCHEMBL9229633 0.83 OGA (0.32)
SCHEMBL3712330 0.78 PYGB (0.47) PYGBPYGLPYGMLMNAGBA1
SCHEMBL7052003 0.78 PYGB (0.47) PYGBPYGLPYGMLMNAGBA1
SCHEMBL3712328 0.78 PYGB (0.47) PYGBPYGLPYGMLMNAGBA1
SCHEMBL3712334 0.77 PYGB (0.46) PYGBPYGLPYGMLMNAGBA1
SCHEMBL3481602 0.77 PYGB (0.46) PYGBPYGLPYGMLMNAGBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0474590-A2 Taurine derivatives, process for their preparation and their use CIBA-GEIGY AG (CH) 1992-03-11 EP claimed
EP-0474590-A2 Taurine derivatives, process for their preparation and their use CIBA-GEIGY AG (CH) 1992-03-11 EP disclosed
US-4912204-A Fluoro-substituted epipodophyllotoxin glucosides BRISTOL-MYERS COMPANY (US) 1990-03-27 US disclosed
EP-0358197-A2 Fluoro-substituted epipodophyllotoxin glucosides Bristol-Myers Squibb Company (US) 1990-03-14 EP disclosed
US-4739043-A REACTING AN ALCOHOL WITH AND ALDOSE IN HYDROGEN FLUORIDE SOLVENT BEGHIN-SAY, S.A. (FR) 1988-04-19 US disclosed