Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGB | P11216 | 8/20 | 0.43 |
| ▸ | PYGL | P06737 | 3/20 | 0.43 |
| ▸ | PYGM | P11217 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9708959 | 1.00 | PYGB (0.43) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL2353972 | 1.00 | PYGB (0.43) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL7742729 | 1.00 | PYGB (0.43) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL9751326 | 0.93 | PYGB (0.37) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL9229633 | 0.83 | OGA (0.32) | — | |
| SCHEMBL3712330 | 0.78 | PYGB (0.47) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL7052003 | 0.78 | PYGB (0.47) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL3712328 | 0.78 | PYGB (0.47) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL3712334 | 0.77 | PYGB (0.46) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL3481602 | 0.77 | PYGB (0.46) | PYGBPYGLPYGMLMNAGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236935-B2 | Gem-difluorinated C-glycoside compounds derived from podophyllotoxin, their preparation and their applications | INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE ROUEN (INSA) (FR) | 2012-08-07 | — | — | US | disclosed |