Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7056051 | 0.81 | CA1 (0.41) | CA1CA2CA7CA9CA4 | |
| SCHEMBL11667403 | 0.72 | MEN1 (0.41) | MEN1LMNAHPGDTSHRBLM | |
| SCHEMBL8734074 | 0.70 | TDP1 (0.36) | TSHRTDP1PKMSMN1; SMN2 | |
| SCHEMBL7051743 | 0.69 | CA1 (0.48) | CA1CA2CA7CA9CA4 | |
| SCHEMBL4443728 | 0.69 | CA1 (0.59) | CA1CA2CA7CA9CA4 | |
| SCHEMBL18604307 | 0.68 | CA1 (0.52) | CA1CA2CA7CA9CA4 | |
| Phosphoric Acid SCHEMBL1074271 | 0.67 | CA1 (0.47) | CA1CA2CA7CA9CA4 | |
| SCHEMBL7057360 | 0.67 | CA1 (0.37) | CA1CA2CA7CA9CA4 | |
| Phosphoric Acid SCHEMBL170152 | 0.66 | CA1 (0.55) | CA1CA2CA7CA9CA4 | |
| SCHEMBL1274601 | 0.66 | CA1 (0.55) | CA1CA2CA7CA9CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792275-B1 | IMPROVED ANTIVIRAL PRODRUGS | UNIV CALIFORNIA (US) | 2004-03-03 | — | — | EP | claimed |
| US-6002029-A | Antiviral prodrugs | CHIMERIX, INC. | 1999-12-14 | — | — | US | claimed |