Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053353 | 0.77 | NR3C1 (0.46) | NR3C1P2RX3P2RX2MEN1KMT2A | |
| SCHEMBL7249278 | 0.77 | NR3C1 (0.62) | NR3C1THRBTHRA | |
| SCHEMBL7250347 | 0.75 | NR3C1 (0.46) | NR3C1GAAP2RX3P2RX2TOP2A | |
| SCHEMBL7251075 | 0.73 | NR3C1 (0.46) | NR3C1GAAP2RX3P2RX2TOP2A | |
| SCHEMBL7052846 | 0.73 | NR3C1 (0.67) | NR3C1GAAALDH1A1MEN1KMT2A | |
| SCHEMBL7250248 | 0.70 | NR3C1 (0.52) | NR3C1TOP2ATOP2BTHRBTHRA | |
| SCHEMBL7250267 | 0.70 | NR3C1 (0.61) | NR3C1THRBTHRA | |
| SCHEMBL11863667 | 0.70 | CNR2 (0.47) | CNR2GAAALDH1A1PKMMEN1 | |
| SCHEMBL7249537 | 0.69 | NR3C1 (0.70) | NR3C1THRBTHRA | |
| SCHEMBL7250117 | 0.69 | NR3C1 (0.62) | NR3C1THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102739-B1 | GLUCOCORTICOID AND THYROID HORMONE RECEPTOR LIGANDS FOR THE TREATMENT OF METABOLIC DISORDERS | KAROBIO AB (SE) | 2003-04-23 | — | — | EP | claimed |