Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.34 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7055432 | 0.85 | NR3C1 (0.73) | NR3C1ALDH1A1KDM4EGAANPC1 | |
| SCHEMBL7052439 | 0.81 | NR3C1 (0.75) | NR3C1ALDH1A1KDM4EGAANPC1 | |
| SCHEMBL7050566 | 0.80 | NR3C1 (0.71) | NR3C1ALDH1A1KDM4EGAANPC1 | |
| SCHEMBL5632584 | 0.80 | NR3C1 (1.00) | NR3C1 | |
| SCHEMBL7050844 | 0.80 | NR3C1 (0.85) | NR3C1ALDH1A1KDM4EGAANPC1 | |
| SCHEMBL5630623 | 0.80 | NR3C1 (0.85) | NR3C1ALDH1A1KDM4EGAANPC1 | |
| SCHEMBL7053031 | 0.79 | NR3C1 (0.83) | NR3C1CTNNB1WNT3A | |
| SCHEMBL7050568 | 0.78 | NR3C1 (0.76) | NR3C1ALDH1A1KDM4EGAANPC1 | |
| SCHEMBL7684969 | 0.75 | NR3C1 (0.88) | NR3C1NPC1RAB9APOLBCTNNB1 | |
| SCHEMBL7052430 | 0.74 | NR3C1 (0.64) | NR3C1ALDH1A1KDM4EGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102739-B1 | GLUCOCORTICOID AND THYROID HORMONE RECEPTOR LIGANDS FOR THE TREATMENT OF METABOLIC DISORDERS | KAROBIO AB (SE) | 2003-04-23 | — | — | EP | claimed |