Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.64 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.64 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7050907 | 0.93 | HTR1A (0.65) | HTR1AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL7051161 | 0.93 | ADRA1D (0.64) | HTR1AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL7049769 | 0.91 | HTR1A (0.63) | HTR1AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL7051822 | 0.91 | HTR1A (0.63) | HTR1AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL8875767 | 0.88 | HTR1A (0.77) | HTR1AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL7050096 | 0.88 | HTR1A (0.63) | HTR1AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL8875520 | 0.88 | HTR1A (0.84) | HTR1AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL8876595 | 0.86 | HTR1A (0.61) | HTR1AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL7051599 | 0.86 | HTR1A (0.61) | HTR1AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| Water SCHEMBL7051533 | 0.85 | HTR1A (0.60) | HTR1AADRA1DADRA1AADRA1BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1222183-B1 | BENZOPYRAN DERIVATIVES | RECORDATI CHEM PHARM (IT) | 2003-04-23 | — | — | EP | claimed |
| EP-1222183-A1 | BENZOPYRAN DERIVATIVES | RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA S.p.a. (IT) | 2002-07-17 | — | — | EP | claimed |
| US-6403594-B1 | UROGENTIAL INFECTIONS, ETC | RECORDATI, S.A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 2002-06-11 | — | — | US | claimed |
| WO-2001029022-A1 | BENZOPYRAN DERIVATIVES | RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA SPA (IT) | 2001-04-26 | — | — | WO | claimed |
| EP-1222183-B1 | BENZOPYRAN DERIVATIVES | RECORDATI CHEM PHARM (IT) | 2003-04-23 | — | — | EP | disclosed |
| US-6403594-B1 | UROGENTIAL INFECTIONS, ETC | RECORDATI, S.A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 2002-06-11 | — | — | US | disclosed |