Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.61 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.61 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8875383 | 0.91 | ADRA1A (0.74) | HTR1AADRA1DADRA1AADRA1BDRD3 | |
| SCHEMBL8876214 | 0.91 | ADRA1A (0.74) | HTR1AADRA1DADRA1AADRA1BDRD3 | |
| SCHEMBL8875386 | 0.90 | HTR1A (0.75) | HTR1AADRA1DADRA1AADRA1BDRD3 | |
| SCHEMBL8875957 | 0.87 | HTR1A (0.77) | HTR1AADRA1DADRA1AADRA1BDRD3 | |
| SCHEMBL7050907 | 0.87 | HTR1A (0.65) | HTR1AADRA1DADRA1AADRA1BTP53 | |
| SCHEMBL8875767 | 0.86 | HTR1A (0.77) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL7051161 | 0.86 | ADRA1D (0.64) | HTR1AADRA1DADRA1AADRA1BTP53 | |
| SCHEMBL7052077 | 0.86 | HTR1A (0.64) | HTR1AADRA1DADRA1AADRA1BTP53 | |
| SCHEMBL7050096 | 0.85 | HTR1A (0.63) | HTR1AADRA1DADRA1AADRA1BTP53 | |
| SCHEMBL8875520 | 0.85 | HTR1A (0.84) | HTR1AADRA1DADRA1AADRA1BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658587-A | TRANSDERMAL PATCH | FLORA INC. (US) | 1997-08-19 | — | — | US | claimed |
| WO-1997014419-A1 | TRANSDERMAL DELIVERY OF ALPHA ADRENOCEPTOR BLOCKING AGENTS | FLORA INC. (US) | 1997-04-24 | — | — | WO | claimed |
| US-5605896-A | Bicyclic heterocyclic derivatives having α1 adrenergic and 5HT1A activities | RECORDATI S.A., CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1997-02-25 | — | — | US | claimed |
| US-5658587-A | TRANSDERMAL PATCH | FLORA INC. (US) | 1997-08-19 | — | — | US | disclosed |
| WO-1997014419-A1 | TRANSDERMAL DELIVERY OF ALPHA ADRENOCEPTOR BLOCKING AGENTS | FLORA INC. (US) | 1997-04-24 | — | — | WO | disclosed |