Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | AGER | Q15109 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | ASPH | Q12797 | 8/20 | 0.36 |
| ▸ | KDM8 | Q8N371 | 8/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.35 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.35 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trimethylammonium SCHEMBL2411026 | 0.93 | KDM4E (0.36) | KDM4EALDH1A1CYP3A4MAPTALOX15 | |
| Pyridine SCHEMBL2410384 | 0.91 | KDM4E (0.41) | KDM4EALDH1A1CYP3A4MAPTALOX15 | |
| Nitric Acid SCHEMBL7047310 | 0.91 | KDM4E (0.34) | KDM4EALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL28174771 | 0.84 | CYP4F2 (0.44) | KDM4EALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL29280504 | 0.84 | CYP4F2 (0.44) | KDM4EALDH1A1MAPTALOX15TSHR | |
| SCHEMBL30530135 | 0.84 | CYP4F2 (0.44) | KDM4EALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL23500803 | 0.83 | GABRP (0.32) | KDM4EASPHKDM8GABRPGABRD | |
| SCHEMBL2486333 | 0.83 | KDM4E (0.41) | KDM4EALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL351540 | 0.81 | GABRP (0.46) | KDM4EALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL2487883 | 0.81 | KDM4E (0.40) | KDM4EALDH1A1CYP3A4MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601288-B1 | Substituted 2,3-dicarboxypyridinium nitrates | BASF AG (DE) | 2003-05-02 | — | — | EP | claimed |
| CN-222076592-U | Acidification kettle for producing 5-methyl-pyridine-2, 3-dicarboxylic acid diethyl ester | 苏州嘉实稳博新能源有限公司 | 2024-11-29 | — | — | CN | disclosed |
| CN-114904474-B | Device and method for reacting diethyl 5-bromomethylpyridine-2, 3-dicarboxylic acid | 内蒙古新农基科技有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-116715626-A | Intermediate for preparing imidazolinone compound (I) and application thereof | 山东先达农化股份有限公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-107216286-B | Preparation method of 5-bromomethyl-2, 3-pyridine dimethyl dicarboxylate | 江苏省农用激素工程技术研究中心有限公司 | 2020-03-31 | — | — | CN | disclosed |
| CN-107235895-A | The method for preparing the dicarboxylic acid derivatives of 5 methoxypicoline 2,3 of substitution | 巴斯夫欧洲公司 | 2017-10-10 | — | — | CN | disclosed |
| CN-107216286-A | The preparation method of the pyridinedicarboxylic acid dimethyl ester of 5 bromomethyl 2,3 | 江苏省农用激素工程技术研究中心有限公司 | 2017-09-29 | — | — | CN | disclosed |
| CN-102245575-B | Process for preparing substituted 5-methoxymethylpyridine-2, 3-dicarboxylic acid derivatives | 巴斯夫欧洲公司 | 2017-07-28 | — | — | CN | disclosed |
| EP-0434965-B1 | Alkyl esters of 5-heterocyclic-pyridine-2,3-dicarboxylic acids and 5-heterocyclic 2-(2-imidazolin-2-yl) pyridines and methods for preparation thereof | AMERICAN CYANAMID CO (US) | 1998-05-20 | — | — | EP | disclosed |
| EP-0548532-B1 | 5,6-Disubstituted-3-pyridylmethyl ammonium halide compounds useful for the preparation of 5-(substituted methyl)-2,3-pyridinedicarboxylic acids | AMERICAN CYANAMID CO (US) | 1997-04-16 | — | — | EP | disclosed |
| US-5288866-A | Chemical intermediates in the preparation of purity herbicides | AMERICAN CYANAMID COMPANY (US) | 1994-02-22 | — | — | US | disclosed |
| US-5283230-A | Pre- and post-emergence herbicides | AMERICAN CYANAMID COMPANY (US) | 1994-02-01 | — | — | US | disclosed |
| US-5239070-A | Herbicide intermediates | AMERICAN CYANAMID COMPANY (US) | 1993-08-24 | — | — | US | disclosed |
| US-5225564-A | Acetalization, amination or sulfiding in a solvent | AMERICAN CYANAMID COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0548532-A1 | 5,6-Disubstituted-3-pyridylmethyl ammonium halide compounds useful for the preparation of 5-(substituted methyl)-2,3-pyridinedicarboxylic acids | AMERICAN CYANAMID COMPANY (US) | 1993-06-30 | — | — | EP | disclosed |
| US-5166060-A | Prepared by the action of 2,3-dihydroxybenzoate-3,4-dioxygenase on 2,3-dihydroxybenzoic acid | CELGENE CORPORATION (US) | 1992-11-24 | — | — | US | disclosed |
| US-5039333-A | 5-heterocyclic 2-(2-imidazolin-2-yl)pyridines, useful as herbicidal agents | AMERICAN CYANAMID COMPANY | 1991-08-13 | — | — | US | disclosed |
| EP-0434965-A2 | Alkyl esters of 5-heterocyclic-pyridine-2,3-dicarboxylic acids and 5-heterocyclic 2-(2-imidazolin-2-yl) pyridines and methods for preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1991-07-03 | — | — | EP | disclosed |
| US-5026859-A | Intermediates for herbicides | AMERICAN CYANAMID COMPANY (US) | 1991-06-25 | — | — | US | disclosed |
| EP-0390102-A2 | Process for the preparation of pyridine-2,3-dicarboxylic acids | CELGENE CORPORATION (US) | 1990-10-03 | — | — | EP | disclosed |