Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10628297 | 0.81 | TAAR1 (0.47) | TAAR1ALDH1A1TSHRKMT2AMAPK1 | |
| SCHEMBL6578455 | 0.75 | ALDH1A1 (0.42) | MEN1ALDH1A1TSHRKMT2AMAPK1 | |
| SCHEMBL11654724 | 0.74 | RIPK1 (0.33) | RIPK1TAAR1SLC6A2MEN1ALDH1A1 | |
| SCHEMBL10318688 | 0.74 | RIPK1 (0.34) | RIPK1TAAR1SLC6A2 | |
| SCHEMBL2272014 | 0.73 | TP53 (0.38) | ALDH1A1TSHRLMNA | |
| SCHEMBL272395 | 0.73 | RIPK1 (0.35) | RIPK1TAAR1SLC6A2MEN1ALDH1A1 | |
| SCHEMBL2272064 | 0.70 | TP53 (0.35) | — | |
| SCHEMBL22730164 | 0.70 | CYP2C19 (0.39) | TAAR1ALDH1A1TSHRKMT2AMAPK1 | |
| SCHEMBL705415 | 0.69 | MAPK1 (0.33) | RIPK1TAAR1SLC6A2ALDH1A1TSHR | |
| SCHEMBL27290628 | 0.69 | LOXL2 (0.38) | TAAR1MEN1ALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985674-B1 | ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR ALPHA-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING ALPHA-OLEFIN POLYMERS | MITSUBISHI CHEM CORP (JP) | 2003-04-23 | — | — | EP | disclosed |
| EP-0980870-B1 | Process for preparing silanes substituted at position alpha of the silicon atom by a tertiary hydrocarbon group | WACKER CHEMIE GMBH (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-6255515-B1 | COORDINATION POLYMERIZATION CATALYSTS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-07-03 | — | — | US | disclosed |
| US-6156918-A | Process for the preparation of silanes, with a tertiary hydrocarbon group in the a-position relative to the silicon atom | WACKER-CHEMIE GMBH (DE) | 2000-12-05 | — | — | US | disclosed |
| EP-0985674-A1 | ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR $g(a)-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING $g(a)-OLEFIN POLYMERS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-03-15 | — | — | EP | disclosed |
| EP-0980870-A1 | Process for preparing silanes substituted at position alpha of the silicon atom by a tertiary hydrocarbon group | Wacker-Chemie GmbH (DE) | 2000-02-23 | — | — | EP | disclosed |
| US-5872274-A | Method for preparation of tertiary-hydrocarbylsilyl compounds | DOW CORNING CORPORATION (US) | 1999-02-16 | — | — | US | disclosed |
| EP-0405560-B2 | Preparation of tertiary-hydrocarbylsilyl compounds | DOW CORNING TORAY SILICONE (JP) | 1998-08-12 | — | — | EP | disclosed |
| US-5068386-A | PREPARATION OF TERTIARY-HYDROCARBYLSILYL COMPOUNDS | DOW CORNING TORAY SILICONE COMPANY, LTD. (JP) | 1991-11-26 | — | — | US | disclosed |
| US-5061817-A | ENOLSILYL ETHER COMPOUND | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-10-29 | — | — | US | disclosed |
| EP-0405560-A2 | Preparation of tertiary-hydrocarbylsilyl compounds | Dow Corning Toray Silicone Company, Limited (JP) | 1991-01-02 | — | — | EP | disclosed |
| EP-0167155-B1 | BETA-LACTAM COMPOUND AND PREPARING THEREOF | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-03-08 | — | — | EP | disclosed |
| US-4791198-A | CHEMICAL INTERMEDIATES FOR THIENAMYCINS | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-12-13 | — | — | US | disclosed |
| EP-0167155-A1 | beta-Lactam compound and preparing thereof | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1986-01-08 | — | — | EP | disclosed |