Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | FABP4 | P15090 | 6/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31381967 | 0.83 | GAA (0.55) | ATMGAAKMT2A | |
| SCHEMBL12916500 | 0.83 | FABP4 (0.51) | ATML3MBTL1FABP4TBXA2RALDH1A1 | |
| SCHEMBL2949015 | 0.82 | FABP4 (0.57) | ATMGAAL3MBTL1FABP4TBXA2R | |
| SCHEMBL27552122 | 0.79 | FABP4 (0.42) | ATMFABP4ALDH1A1 | |
| SCHEMBL6186899 | 0.77 | CYP3A4 (0.54) | ATML3MBTL1KMT2AALDH1A1TSHR | |
| SCHEMBL1200801 | 0.75 | ALDH1A1 (0.75) | ATMGAATBXA2RALDH1A1 | |
| SCHEMBL9778050 | 0.75 | GAA (0.48) | GAAL3MBTL1KMT2ATBXA2RALDH1A1 | |
| SCHEMBL27571698 | 0.75 | ALDH1A1 (0.43) | ATML3MBTL1KMT2AFABP4ALDH1A1 | |
| SCHEMBL2945116 | 0.75 | TBXA2R (0.66) | GAAFABP4TBXA2RALDH1A1TSHR | |
| SCHEMBL6762534 | 0.75 | SLC1A3 (0.48) | ATMGAAL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307226-A2 | VITRONECTIN RECEPTOR ANTAGONIST PHARMACEUTICALS | Bristol-Myers Squibb Pharma Company (US) | 2003-05-07 | — | — | EP | claimed |
| WO-2001097848-A2 | VITRONECTIN RECEPTOR ANTAGONIST PHARMACEUTICALS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2001-12-27 | — | — | WO | claimed |
| EP-1307226-A2 | VITRONECTIN RECEPTOR ANTAGONIST PHARMACEUTICALS | Bristol-Myers Squibb Pharma Company (US) | 2003-05-07 | — | — | EP | disclosed |
| WO-2001097848-A2 | VITRONECTIN RECEPTOR ANTAGONIST PHARMACEUTICALS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2001-12-27 | — | — | WO | disclosed |