SCHEMBL7052852

SCHEMBL7052852

CCCOCCC(=O)O[SiH3]

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
DGKA P23743 1/20 0.34
HSD17B10 Q99714 1/20 0.33
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
NAAA Q02083 1/20 0.30
EPHX2 P34913 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7055152 0.84
SCHEMBL13502929 0.79 ALDH1A1 (0.39) ALDH1A1DGKAHSD17B10CES2CES1
SCHEMBL7054494 0.79
SCHEMBL443342 0.79 DGKA (0.50) ALDH1A1DGKANAAA
SCHEMBL445490 0.79 TSHR (0.55) ALDH1A1DGKAHSD17B10TSHR
SCHEMBL12504354 0.78 TSHR (0.46) ALDH1A1DGKACES2NAAATSHR
SCHEMBL49604 0.78
SCHEMBL27834334 0.77 DGKA (0.48) ALDH1A1DGKANAAA
SCHEMBL13699511 0.77 TSHR (0.52) ALDH1A1DGKAHSD17B10TSHR
SCHEMBL15308045 0.77 TSHR (0.52) ALDH1A1DGKAHSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1006118-B1 Method for synthesizing organosilicon compounds that contain a group bonded to silicon across the SI-C bond DOW CORNING ASIA LTD (JP) 2003-05-07 EP disclosed
EP-1085022-A1 A method of manufacturing an acyloxysilane compound having functional groups bonded to silicon atoms via Si-C- bonds Dow Corning Asia, Ltd. (JP) 2001-03-21 EP disclosed
US-6175031-B1 PLATINUM-CATALYZED HYDROSILYLATION BETWEEN SIH-SUBSTITUTED SILICON COMPOUNDS AND UNSATURATED GROUP-FUNCTIONAL ORGANIC OR ORGANOSILICON COMPOUNDS IN PRESENCE OF A (ACYLOXY)-FUNCTIONAL HYDROGENSILANE COMPOUND OR ACID AND HYDRO(ALKOXY)SILANE DOW CORNING ASIA, LTD. (JP) 2001-01-16 US disclosed
US-6111126-A Method for synthesizing organosilicon compounds that contain a functional group bonded to silicon across the Si-C bond DOW CORNING ASIA, LTD. (JP) 2000-08-29 US disclosed
EP-1006118-A2 Method for synthesizing organosilicon compounds that contain a group bonded to silicon across the SI-C bond Dow Corning Asia, Ltd. (JP) 2000-06-07 EP disclosed
US-6060620-A Method for manufacturing an acyloxysilane compound having functional groups bonded to silicon atoms via SI--C bonds DOW CORNING ASIA, LTD. (JP) 2000-05-09 US disclosed