Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31556208 | 1.00 | MAOB (0.45) | MAOBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8876175 | 0.78 | ALOX15 (0.58) | MAOBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11797746 | 0.75 | TTR (0.51) | MAOBALDH1A1HPGDNR4A1NR4A2 | |
| SCHEMBL18235035 | 0.75 | MAOB (0.44) | MAOBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL23360189 | 0.75 | MCL1 (0.51) | MAOBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL31491647 | 0.75 | ALB (0.47) | MAOBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11538924 | 0.75 | CES1 (0.42) | MAOBALDH1A1NR4A2CES1TTR | |
| SCHEMBL8876297 | 0.74 | CYSLTR1 (0.45) | MAOBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11621083 | 0.74 | MCL1 (0.46) | KDM4EALDH1A1HPGDHSD17B10MCL1 | |
| SCHEMBL31034958 | 0.73 | CES1 (0.38) | MAOBKDM4ECES1GLASTING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1222183-B1 | BENZOPYRAN DERIVATIVES | RECORDATI CHEM PHARM (IT) | 2003-04-23 | — | — | EP | claimed |
| EP-1222183-A1 | BENZOPYRAN DERIVATIVES | RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA S.p.a. (IT) | 2002-07-17 | — | — | EP | claimed |
| WO-2001029022-A1 | BENZOPYRAN DERIVATIVES | RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA SPA (IT) | 2001-04-26 | — | — | WO | claimed |