Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | GALR3 | O60755 | 2/20 | 0.38 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.38 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | MPL | P40238 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10547068 | 0.81 | HNF4A (0.50) | ALDH1A1PSMD14DHODHGALR3NR2F2 | |
| SCHEMBL11619785 | 0.80 | ALOX15 (0.51) | MCL1ALDH1A1PSMD14DHODHTP53 | |
| SCHEMBL11623441 | 0.79 | GPR35 (0.44) | ALDH1A1CYP1A2PSMD14DHODHKDM4E | |
| SCHEMBL11621112 | 0.78 | PSMD14 (0.56) | ALDH1A1CYP1A2PSMD14GALR3CYSLTR1 | |
| SCHEMBL269897 | 0.75 | MCL1 (0.57) | MCL1ALDH1A1CYP1A2ACMSDCAMKK2 | |
| SCHEMBL11624494 | 0.74 | ALDH1A1 (0.37) | ALDH1A1CYP1A2KDM4EHPGDHSD17B10 | |
| SCHEMBL31556208 | 0.74 | MAOB (0.45) | MCL1ALDH1A1MYCKDM4EHPGD | |
| SCHEMBL7052889 | 0.74 | MAOB (0.45) | MCL1ALDH1A1MYCKDM4EHPGD | |
| SCHEMBL8876175 | 0.71 | ALOX15 (0.58) | ALDH1A1DHODHKDM4EHPGDHSD17B10 | |
| SCHEMBL24183987 | 0.71 | MCL1 (0.61) | MCL1ALDH1A1CYP1A2CAMKK2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4124603-A | ANTIMICROBIAL | RIKER LABORATORIES, INC. (US) | 1978-11-07 | — | — | US | disclosed |
| US-4067993-A | Antimicrobial 2-nitro-3-phenylbenzofurancarboxylic acids | RIKER LABORATORIES, INC. (US) | 1978-01-10 | — | — | US | disclosed |