SCHEMBL7052917

SCHEMBL7052917

O=C(O)c1ncccc1Oc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
MAPT P10636 3/20 0.52
KDM4E B2RXH2 2/20 0.52
TSHR P16473 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
CYP3A4 P08684 1/20 0.52
ALOX15 P16050 1/20 0.52
BLM P54132 1/20 0.52
AGER Q15109 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
CTNNB1 P35222 1/20 0.47
TDP1 Q9NUW8 1/20 0.46
CYP1A2 P05177 1/20 0.46
MAPK1 P28482 1/20 0.44
HSD17B10 Q99714 1/20 0.44
HTT P42858 1/20 0.44
TTR P02766 1/20 0.44
KMT2A Q03164 2/20 0.43
TSPO P30536 1/20 0.42
MYC P01106 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2424045 0.88 KMT2A (0.48) ALDH1A1MAPTKDM4ETSHRL3MBTL1
SCHEMBL10712243 0.87 RAB9A (0.51) ALDH1A1MAPTKDM4ETSHRL3MBTL1
SCHEMBL726400 0.86 CTNNB1 (0.57) ALDH1A1KDM4ETSHRCTNNB1TDP1
SCHEMBL7054642 0.86 TSHR (0.45) ALDH1A1MAPTKDM4ETSHRL3MBTL1
SCHEMBL3699328 0.86 CTNNB1 (0.45) ALDH1A1MAPTKDM4ETSHRL3MBTL1
SCHEMBL2553504 0.84 MAPT (0.51) ALDH1A1MAPTKDM4ETSHRL3MBTL1
SCHEMBL547649 0.84 KDM4E (0.53) ALDH1A1MAPTKDM4ETSHRL3MBTL1
SCHEMBL10720008 0.83 CTNNB1 (0.42) ALDH1A1TSHRCTNNB1TDP1MAPK1
SCHEMBL11170285 0.83 TDP1 (0.60) ALDH1A1MAPTKDM4ETSHRL3MBTL1
SCHEMBL4425717 0.83 KDM4E (0.57) ALDH1A1MAPTKDM4ETSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113729027-A Fluopyramide-isoproturon suspending agent and production process thereof 池州飞昊达化工有限公司 2021-12-03 CN claimed
US-6200933-B1 LOW TOXICITY TO HUMANS AND CATTLE KUREHA KAGAKU KABUSHIKI KAISHA (JP) 2001-03-13 US claimed
EP-0949248-A1 6-(NONSUBSTITUTED OR SUBSTITUTED) PHENOXYPICOLINIC ACIDS, PROCESS OF PREPARING THE SAME, AND AGRICULTURAL/HORTICULTURAL GERMICIDES CONTAINING THE SAME KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1999-10-13 EP claimed
JP-4290805-A None JP disclosed
CN-118948847-A Sorafenib pharmaceutical composition and preparation method thereof 杭州华东医药集团新药研究院有限公司 2024-11-15 CN disclosed
CN-114099506-B Pharmaceutical composition containing sorafenib 杭州华东医药集团新药研究院有限公司 2023-03-21 CN disclosed
CN-114295743-A Analytical detection method for 1 and 6 related substances of sorafenib intermediate 福建南方济民医药研发中心有限公司 2022-04-08 CN disclosed
CN-113729027-A Fluopyramide-isoproturon suspending agent and production process thereof 池州飞昊达化工有限公司 2021-12-03 CN disclosed
EP-0949248-B1 6-(NONSUBSTITUTED OR SUBSTITUTED) PHENOXYPICOLINIC ACIDS, PROCESS OF PREPARING THE SAME, AND AGRICULTURAL/HORTICULTURAL GERMICIDES CONTAINING THE SAME KUREHA CHEMICAL IND CO LTD (JP) 2003-10-08 EP disclosed
EP-0949248-B1 6-(NONSUBSTITUTED OR SUBSTITUTED) PHENOXYPICOLINIC ACIDS, PROCESS OF PREPARING THE SAME, AND AGRICULTURAL/HORTICULTURAL GERMICIDES CONTAINING THE SAME KUREHA CHEMICAL IND CO LTD (JP) 2003-10-08 EP disclosed
EP-0882715-B1 NOVEL N-(UNSUBSTITUTED OR SUBSTITUTED)-4-SUBSTITUTED-6-(UNSUBSTITUTED OR SUBSTITUTED)PHENOXY-2-PYRIDINECARBOXAMIDES OR THIOCARBOXAMIDES, PROCESSES FOR PRODUCING THE SAME, AND HERBICIDES KUREHA CHEMICAL IND CO LTD (JP) 2003-04-23 EP disclosed
US-5366956-A Herbicidal acrylonitrile derivatives SHELL RESEARCH LIMITED (GB) 1994-11-22 US disclosed
US-5294597-A 2-((Halophenyl)amido-)m,6-((halophenyl)oxy-)pyridines SHELL RESEARCH LIMITED (GB) 1994-03-15 US disclosed
JP-H04290805-A HERBICIDAL CARBOXAMIDE DERIVATIVE SHELL INTERNATL RES MAATSCHAPPIJ BV 1992-10-15 JP disclosed
CN-1061776-A Benzamide type derivative with herbicide effect SHELL INT RESEARCH (NL) 1992-06-10 CN disclosed
EP-0488474-A1 Herbicidal carboxamide derivatives SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-06-03 EP disclosed
CN-1054974-A The carboxamides derivatives of weeding SHELL INT RESEARCH (NL) 1991-10-02 CN disclosed
EP-0447004-A2 Herbicidal carboxamide derivatives SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1991-09-18 EP disclosed
EP-0434132-A2 Herbicidal acrylonitrile derivatives SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1991-06-26 EP disclosed
US-4764522-A ANTIDEPRESSANT, ANTIPARKINSON DISEASE HOFFMANN-LA ROCHE INC. (US) 1988-08-16 US disclosed