Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | AGER | Q15109 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TSPO | P30536 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052917 | 0.86 | ALDH1A1 (0.52) | CTNNB1TDP1ALDH1A1MAPK1HSD17B10 | |
| SCHEMBL726400 | 0.83 | CTNNB1 (0.57) | CTNNB1TDP1ALDH1A1MAPK1HSD17B10 | |
| SCHEMBL7054642 | 0.83 | TSHR (0.45) | CTNNB1TDP1ALDH1A1MAPK1HSD17B10 | |
| SCHEMBL11170285 | 0.81 | TDP1 (0.60) | CTNNB1TDP1ALDH1A1MAPK1HSD17B10 | |
| SCHEMBL10720008 | 0.81 | CTNNB1 (0.42) | CTNNB1TDP1ALDH1A1MAPK1HSD17B10 | |
| SCHEMBL7642204 | 0.78 | ALDH1A1 (0.58) | ALDH1A1MAPK1HSD17B10TSHRKMT2A | |
| SCHEMBL7055885 | 0.77 | GCK (0.41) | CTNNB1TDP1ALDH1A1MAPK1HSD17B10 | |
| SCHEMBL9645777 | 0.76 | TDP1 (0.48) | CTNNB1TDP1ALDH1A1MAPK1HSD17B10 | |
| SCHEMBL2424045 | 0.75 | KMT2A (0.48) | ALDH1A1TSHRL3MBTL1KMT2AMAPT | |
| SCHEMBL27564839 | 0.75 | CTNNB1 (0.51) | CTNNB1TDP1ALDH1A1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101896507-B | Catalyst compounds and their use | EXXONMOBIL CHEM PATENTS INC | 2012-11-28 | — | — | CN | disclosed |
| US-7767773-B2 | Catalyst compounds are use thereof | EXXONMOBILE CHEMICAL PATENTS INC. (US) | 2010-08-03 | — | — | US | disclosed |
| EP-2112173-A1 | Catalyst compounds and use thereof | ExxonMobil Chemical Patents Inc. (US) | 2009-10-28 | — | — | EP | disclosed |
| US-20080182952-A1 | Catalyst Compounds And Use Thereof | EXXONMOBIL CHEMICAL PATENTS INC. | 2008-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080182952-A1 | Catalyst Compounds And Use Thereof | HACL2, AHCYL1, CRKL | CTNNB1 403/4885TDP1 4535/4885ALDH1A1 3779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.