SCHEMBL726400

SCHEMBL726400

NC(=O)c1ncccc1Oc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CTNNB1 P35222 1/20 0.57
SMN1; SMN2 Q16637 2/20 0.48
PARP10 Q53GL7 2/20 0.47
ALDH1A1 P00352 2/20 0.47
TDP1 Q9NUW8 1/20 0.44
RAB9A P51151 1/20 0.43
KDM4E B2RXH2 1/20 0.43
SCN9A Q15858 1/20 0.43
MAPK1 P28482 1/20 0.43
HSD17B10 Q99714 1/20 0.43
USP2 O75604 1/20 0.42
KMT2A Q03164 1/20 0.42
ADRA2C P18825 1/20 0.42
TSHR P16473 1/20 0.42
BRD4 O60885 1/20 0.42
ICAM1 P05362 1/20 0.42
SELE P16581 1/20 0.42
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27564839 0.88 CTNNB1 (0.51) CTNNB1SMN1; SMN2PARP10ALDH1A1TDP1
SCHEMBL7052917 0.86 ALDH1A1 (0.52) CTNNB1ALDH1A1TDP1RAB9AKDM4E
SCHEMBL20176683 0.86 RAB9A (0.43) CTNNB1SMN1; SMN2PARP10ALDH1A1RAB9A
SCHEMBL3699328 0.83 CTNNB1 (0.45) CTNNB1ALDH1A1TDP1RAB9AKDM4E
SCHEMBL7054642 0.83 TSHR (0.45) CTNNB1ALDH1A1TDP1RAB9AKDM4E
SCHEMBL3700394 0.83 KDM4E (0.54) CTNNB1SMN1; SMN2PARP10ALDH1A1RAB9A
SCHEMBL12500943 0.81 CTNNB1 (0.50) CTNNB1SMN1; SMN2PARP10ALDH1A1SCN9A
SCHEMBL11170285 0.81 TDP1 (0.60) CTNNB1SMN1; SMN2ALDH1A1TDP1RAB9A
SCHEMBL10720008 0.81 CTNNB1 (0.42) CTNNB1SMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL8441797 0.79 KMT2A (0.60) SMN1; SMN2KDM4EUSP2KMT2AICAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4749647-B2 2011-08-17 JP claimed
EP-1464223-B1 Synergistic herbicidal mixtures BASF AG (DE) 2006-08-23 EP claimed
EP-1346638-B1 Herbicidal compositions BAYER CROPSCIENCE SA (FR) 2005-12-28 EP claimed
EP-1267612-B1 SYNERGISTIC HERBICIDAL MIXTURES BASF AG (DE) 2004-11-03 EP claimed
EP-1464223-A1 Synergistic herbicidal mixtures BASF AKTIENGESELLSCHAFT (DE) 2004-10-06 EP claimed
US-6660692-B1 Herbicidal compositions comprising picolinafen AVENTIS CROPSCIENCE S.A. (FR) 2003-12-09 US claimed
US-6645911-B2 Using a 6-phenoxypyridyl-2-yl carboxamide compound BASF AKTIENGESELLSCHAFT (DE) 2003-11-11 US claimed
EP-1189510-B1 NEW HERBICIDAL COMPOSITIONS BAYER CROPSCIENCE SA (FR) 2003-10-01 EP claimed
JP-2003528893-A 2003-09-30 JP claimed
EP-1346638-A1 Herbicidal compositions Bayer CropScience S.A. (FR) 2003-09-24 EP claimed
EP-0882715-B1 NOVEL N-(UNSUBSTITUTED OR SUBSTITUTED)-4-SUBSTITUTED-6-(UNSUBSTITUTED OR SUBSTITUTED)PHENOXY-2-PYRIDINECARBOXAMIDES OR THIOCARBOXAMIDES, PROCESSES FOR PRODUCING THE SAME, AND HERBICIDES KUREHA CHEMICAL IND CO LTD (JP) 2003-04-23 EP claimed
EP-1267612-A1 SYNERGISTIC HERBICIDAL MIXTURES BASF AKTIENGESELLSCHAFT (DE) 2003-01-02 EP claimed
EP-1189510-A1 NEW HERBICIDAL COMPOSITIONS AVENTIS CROPSCIENCE S.A. (FR) 2002-03-27 EP claimed
US-20020028747-A1 Synergistic herbicidal mixtures BASF AKTIENGESELLSCHAFT (DE) 2002-03-07 US claimed
US-6339045-B1 CAN BE USED IN A SMALL AMOUNT, SHOWING A GOOD SELECTIVITY BETWEEN CROP AND WEED, AND CAUSING NO PHYTOTOXICITY KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2002-01-15 US claimed
WO-2001074157-A2 SYNERGISTIC HERBICIDAL MIXTURES BASF AG (DE) 2001-10-11 WO claimed
WO-2000078147-A1 NEW HERBICIDAL COMPOSITIONS AVENTIS CROPSCIENCE S.A. (FR) 2000-12-28 WO claimed
EP-0882715-A1 NOVEL N-(UNSUBSTITUTED OR SUBSTITUTED)-4-SUBSTITUTED-6-(UNSUBSTITUTED OR SUBSTITUTED)PHENOXY-2-PYRIDINECARBOXAMIDES OR THIOCARBOXAMIDES, PROCESSES FOR PRODUCING THE SAME, AND HERBICIDES KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1998-12-09 EP claimed
EP-4175714-A1 RIP1K INHIBITORS Rigel Pharmaceuticals, Inc. (US) 2023-05-10 EP disclosed
EP-0447004-A2 Herbicidal carboxamide derivatives SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1991-09-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020028747-A1 Synergistic herbicidal mixtures CACNA1F, THRA, CA5A CTNNB1 4550/4885SMN1; SMN2 2497/4885PARP10 3315/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.