SCHEMBL7052922

SCHEMBL7052922

[NH]C(=O)c1cc[nH]c(=O)n1

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
ACMSD Q8TDX5 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
DYRK1A Q13627 1/20 0.32
ADORA2A P29274 1/20 0.32
ADORA1 P30542 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4102491 0.81 KDM4E (0.48) KDM4EALOX15TSHRACMSDTDP1
SCHEMBL2787055 0.79 PDPK1 (0.39) DYRK1A
SCHEMBL4112718 0.76 P2RX7 (0.49) KDM4EDYRK1A
SCHEMBL2785730 0.76 MAPK1 (0.42) KDM4E
Pyrrole SCHEMBL12467466 0.72 PDPK1 (0.38)
Pyrazole SCHEMBL4098397 0.69 KDM4E (0.40) KDM4EALOX15TSHRACMSDTDP1
Uracil SCHEMBL80962 0.69
SCHEMBL10533260 0.68 ALDH1A1 (0.46) KDM4ETSHRTDP1
SCHEMBL790683 0.67
Uracil SCHEMBL27846109 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003028739-A2 COMPOSITION FOR PREVENTING OR TREATING HYPERLIPIDEMIA OR HYPERGLYCEMIA COMPRISING A POLYMER OR ITS SALT FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2003-04-10 WO disclosed
WO-2002032974-A2 POLYMER AND ITS USE FOR THE TREATMENT AND/OR PREVENTION OF HYPERPHOSPHOREMIA FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-04-25 WO disclosed